RTN4R and RTN4IP1

Number of citations of the paper that reports this interaction (PMID 12160746)
84

Data Source:
HPRD (in vitro)

		RTN4R	RTN4IP1
Gene Name		reticulon 4 receptor	reticulon 4 interacting protein 1
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Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Cell Surface Growth Cone Anchored Component Of Membrane Extracellular Vesicular Exosome	Mitochondrion
	Molecular Function	Receptor Activity Protein Binding	Zinc Ion Binding Oxidoreductase Activity
	Biological Process	Axonogenesis Neurotrophin TRK Receptor Signaling Pathway Regulation Of Axonogenesis Negative Regulation Of Axonogenesis	Oxidation-reduction Process
Pathways		Signalling by NGF Axonal growth inhibition (RHOA activation) p75NTR regulates axonogenesis p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: LINGO1 MAG NGFR OMG RTN4 RTN4IP1	7 interactors: CALCOCO2 EXOC7 RTN4 RTN4R WBP11 WIBG ZYX
Entrez ID		65078	84816
HPRD ID		16123	18008
Ensembl ID		ENSG00000040608
Uniprot IDs		Q9BZR6	G3V1R2 Q8WWV3
PDB IDs		1OZN 1P8T	2VN8
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Axonogenesis Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Projection Organization Regulation Of Axonogenesis Negative Regulation Of Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Neurogenesis Negative Regulation Of Cell Development Regulation Of Neuron Projection Development Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Neuron Differentiation Cellular Response To Growth Factor Stimulus Response To Growth Factor Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Neurogenesis Negative Regulation Of Cell Differentiation Regulation Of Cell Development Enzyme Linked Receptor Protein Signaling Pathway Generation Of Neurons Regulation Of Cell Differentiation Neurogenesis Cellular Response To Organic Substance Neuron Projection Development Regulation Of Cellular Component Organization Neuron Development Central Nervous System Development Nervous System Development Neuron Differentiation Response To Organic Substance Cell Projection Organization Cell Surface Receptor Signaling Pathway Cell Differentiation Cell Development Regulation Of Cell Size Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Hair Follicle Development Regulation Of Branching Morphogenesis Of A Nerve System Development Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Hair Cycle Multicellular Organismal Development Endoplasmic Reticulum Tubular Network Organization Anatomical Structure Development Regulation Of Developmental Growth Signal Transduction Locomotion Positive Regulation Of Odontogenesis	Negative Regulation Of Axonogenesis Negative Regulation Of Cell Morphogenesis Involved In Differentiation Cellular Response To Growth Factor Stimulus Negative Regulation Of Neuron Projection Development Response To Growth Factor Negative Regulation Of Cell Projection Organization Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Axonogenesis Negative Regulation Of Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin Signaling Pathway Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Neurogenesis Response To Organic Substance Negative Regulation Of Cell Development Stress Fiber Assembly
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