PCGF1 and CBX7

Number of citations of the paper that reports this interaction (PMID 21282530)
11

Data Source:
BioGRID (pull down)

		PCGF1	CBX7
Gene Name		polycomb group ring finger 1	chromobox homolog 7
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex	Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm Cytoplasm PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Zinc Ion Binding	Chromatin Binding Single-stranded RNA Binding Protein Binding Methylated Histone Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone H2A Monoubiquitination	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Chromatin Modification Sebaceous Gland Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: BCORL1 CALCOCO2 CBX6 CBX7 CBX8 PCGF5 RING1 RNF125 RNF2 TRIM55 UBE2U	11 interactors: B3GNT5 BMI1 HIST3H3 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 RING1 RNF2 SUV39H2
Entrez ID		84759	23492
HPRD ID		11404	12234
Ensembl ID			ENSG00000100307
Uniprot IDs		Q9BSM1	B0QYP2 O95931
PDB IDs		4HPL 4HPM	2K1B 2L12 2L1B 3GS2
Enriched GO Terms of Interacting Partners?		Histone Ubiquitination Chromatin Modification Chromatin Organization Chromosome Organization Protein Ubiquitination Protein Modification By Small Protein Conjugation Histone H2A Monoubiquitination Histone H2A Ubiquitination Transcription, DNA-templated Histone Modification RNA Biosynthetic Process Histone Monoubiquitination Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Organelle Organization Protein Monoubiquitination RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Histone H2A-K119 Monoubiquitination Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Anterior/posterior Pattern Specification Sebaceous Gland Development Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Protein Modification Process Pattern Specification Process Negative Regulation Of Type I Interferon Production Gastrulation With Mouth Forming Second Regulation Of Metabolic Process Anterior/posterior Axis Specification Cellular Protein Metabolic Process	Histone Ubiquitination Histone Modification Histone H2A Monoubiquitination Histone H2A Ubiquitination Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Chromosome Organization Macromolecule Biosynthetic Process Histone Monoubiquitination Chromatin Modification Chromatin Organization RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Protein Monoubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Protein Ubiquitination Negative Regulation Of Transcription, DNA-templated Anterior/posterior Pattern Specification Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Protein Modification By Small Protein Conjugation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Pattern Specification Process Cellular Metabolic Process Organelle Organization Negative Regulation Of Cellular Metabolic Process Cellular Protein Modification Process Peptidyl-lysine Modification Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Histone H2A-K119 Monoubiquitination Cellular Protein Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Positive Regulation Of Immature T Cell Proliferation In Thymus
Tagcloud ?		bcl6 bcor bcorl1 comprises corepressor demethylase diagnosing estimating eukaryotes h3k36me2 inactivating islands kdm2b lenz massively medulloblastoma microphthalmia monoubiquitylation myelomonocytic nonmethylated oculofaciocardiodental perspective polycomb proposes removes ring1b rnf2 silence uniquely	able acquisition acts carcinomas chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played polycomb progressively relation repressive spp1 suppose take transcriptional whose
Tagcloud (Difference) ?		bcl6 bcor bcorl1 comprises corepressor demethylase diagnosing estimating eukaryotes h3k36me2 inactivating islands kdm2b lenz massively medulloblastoma microphthalmia monoubiquitylation myelomonocytic nonmethylated oculofaciocardiodental perspective proposes removes ring1b rnf2 silence uniquely	able acquisition acts carcinomas chemokine contributing counteracts decreases encoding fact hmga1b inducing interacting interferes involves malignant member modulation osteopontin played progressively relation repressive spp1 suppose take transcriptional whose
Tagcloud (Intersection) ?		polycomb