CBX2 and RYBP

Number of citations of the paper that reports this interaction (PMID 10369680)
44

Data Source:
HPRD (in vivo, in vitro)

		CBX2	RYBP
Gene Name		chromobox homolog 2	RING1 and YY1 binding protein
Image
Gene Ontology Annotations	Cellular Component	Euchromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleoplasm Cytoplasm PcG Protein Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Methylated Histone Binding	DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Chromatin Modification Cell Differentiation Development Of Primary Sexual Characteristics	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Apoptotic Process Multicellular Organismal Development Histone H2A Monoubiquitination
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS			Height ( 20881960 23563607)
Protein-Protein Interactions		12 interactors: DHX57 HIST3H3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP2-4 KRTAP4-12 MDFI RBMY1A1 RBMY1F RYBP	17 interactors: ABL1 CASP10 CASP8 CBX2 E2F2 E2F3 E2F4 E2F6 FADD GABPB1 GABPB2 MDM2 RING1 RNF2 SOCS2 YY1 ZFP42
Entrez ID		84733	23429
HPRD ID		14397	09607
Ensembl ID		ENSG00000173894
Uniprot IDs		Q14781	Q8N488
PDB IDs		2D9U 3H91	3IXS
Enriched GO Terms of Interacting Partners?		RNA Processing	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter TRAIL-activated Apoptotic Signaling Pathway RNA Metabolic Process Cell Cycle Gene Expression Apoptotic Signaling Pathway Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To UV-C Histone H2A Monoubiquitination Positive Regulation Of Macrophage Differentiation Negative Regulation Of Necroptotic Process Apoptotic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Programmed Cell Death Negative Regulation Of Necrotic Cell Death Histone H2A Ubiquitination Positive Regulation Of Gene Expression Regulation Of Necroptotic Process Cell Death Death Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Metabolic Process Organelle Organization Regulation Of Necrotic Cell Death Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		aberrations addressing averaged cdkn2a chromobox cosmic databases discovered exceeded genotranscriptomic inactivating modifiers neoplasms never oncogenic oncomine pcg polycomb rationale silence spanning suggestive tendency transcriptionally transcriptomic tumours unbiased uncharacterised widespread	3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful foxp1 hidden incurable pc pten ptenloxp rapidcap recreate reside sensitized shq1 trp53 trp53loxp unmet validation
Tagcloud (Difference) ?		aberrations addressing averaged cdkn2a chromobox cosmic databases discovered exceeded genotranscriptomic inactivating modifiers neoplasms never oncogenic oncomine pcg polycomb rationale silence spanning suggestive tendency transcriptionally transcriptomic tumours unbiased uncharacterised widespread	3p amplifications breeding classic consuming cooperates costly daunting drive drivers driving endogenously engineering faithful foxp1 hidden incurable pc pten ptenloxp rapidcap recreate reside sensitized shq1 trp53 trp53loxp unmet validation
Tagcloud (Intersection) ?