BEX2 and KNSTRN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BEX2	KNSTRN
Description		brain expressed X-linked 2	kinetochore localized astrin (SPAG5) binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromosome, Centromeric Region Kinetochore Spindle Pole Ruffle Nucleus Chromosome Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Plasma Membrane Centriolar Satellite Microtubule Plus-end Mitotic Spindle
	Molecular Function	Signaling Receptor Binding Protein Binding Metal Ion Binding Molecular Function Inhibitor Activity	Protein Binding Protein Homodimerization Activity Microtubule Plus-end Binding
	Biological Process	Apoptotic Process Signal Transduction Negative Regulation Of Protein Ubiquitination Regulation Of Apoptotic Process Regulation Of Cell Cycle	Mitotic Sister Chromatid Segregation Microtubule Cytoskeleton Organization Spindle Organization Chromosome Segregation Cell Migration Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cellular Response To Epidermal Growth Factor Stimulus
Pathways
Drugs
Diseases
GWAS			Heschl's gyrus morphology ( 25130324) Malaria ( 31844061)
Interacting Genes		92 interacting genes: AKAP9 AURKA BCAR3 BLZF1 BORCS6 BRMS1 CCDC197 CCDC57 CCDC85B CCDC88B CDR2 CEP70 COG4 CTAG1A CTAG1B CYSRT1 EXOC8 FGFR2 FSD2 FST GPRASP3 HSF2BP HSPB2 HSPB2-C11orf52 KLHL20 KNSTRN KRT15 KRT19 KRT27 KRT31 KRT34 KRT38 KRT39 KRT40 KRT6A KRT75 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP21-2 KRTAP3-3 KRTAP4-12 KRTAP5-9 KRTAP6-2 KRTAP6-3 LCN2 LDOC1 LMO2 LZTS2 MAGEA11 MAGEA2 MAGEA2B MAGEA4 MDFI MIPOL1 MKRN3 MORN3 MRPL38 MSS51 MTUS2 NECAB2 NFKBID OIP5 OMP PIK3CA PLA2G10 PLEKHG4 PNMA1 PPM1D PRDM14 PTPN11 ROPN1L SERTAD3 SPRED1 SPRY3 SSX2IP SYCE1 TACC3 TRAF1 TRAF2 TRIM27 TRIM42 TRIM69 TRIM73 TRIP6 USHBP1 VHL VPS28 ZDHHC17 ZNF19	17 interacting genes: ABI2 BEX2 CHMP1B CLU HSPB1 IFT20 MAPK6 MAPRE1 MAPRE3 MECOM MPHOSPH6 NUPR1 OIP5 PALS2 PPL WASHC3 ZDHHC17
Entrez ID		84707	90417
HPRD ID		06484	12669
Ensembl ID		ENSG00000133134	ENSG00000128944
Uniprot IDs		Q9BXY8	Q9Y448
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Protein Binding Cytoskeleton Organization Supramolecular Fiber Organization Cytosol Morphogenesis Of An Epithelium Hair Follicle Morphogenesis Cytoskeleton Identical Protein Binding Epithelial Cell Differentiation Tissue Morphogenesis Negative Regulation Of Protein Acetylation Microtubule Organizing Center Anatomical Structure Morphogenesis Organelle Organization Keratinization	Mitotic Spindle Astral Microtubule End Regulation Of Organelle Organization Regulation Of Supramolecular Fiber Organization Intracellular Protein Localization Cellular Component Assembly Regulation Of Cytoskeleton Organization Protein Localization To Microtubule Microtubule Plus-end Binding Regulation Of Cellular Component Organization Protein Serine/threonine Kinase Binding Microtubule Plus-end Cytoskeleton Spindle Midzone Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Transport Regulation Of Actin Nucleation Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Supramolecular Fiber Organization Perinuclear Endoplasmic Reticulum Lumen Establishment Of Protein Localization Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Neuronal Signal Transduction Negative Regulation Of Protein Kinase C Signaling Identical Protein Binding Positive Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Cell Division Protein Localization To Astral Microtubule Perforant Pathway To Dendrate Granule Cell Synapse Regulation Of Autophagosome Assembly Protein Localization To Cytoskeleton Regulation Of Dendritic Spine Development Positive Regulation Of Cellular Component Biogenesis Cornified Envelope Cytoplasmic Microtubule Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Neurofibrillary Tangle Assembly Protein-containing Complex Organization Septin Cytoskeleton Actin Polymerization Or Depolymerization Zonula Adherens Assembly Protein Localization To Mitotic Spindle Regulation Of Microtubule Polymerization Protein Localization To Spindle Microtubule Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Regulation Of Vacuole Organization Regulation Of Organelle Assembly Opsin Transport Intraciliary Transport Particle
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