SPECC1L and KIAA0368

Number of citations of the paper that reports this interaction (PMID 20682791)
15

Data Source:
BioGRID (two hybrid)

		SPECC1L	KIAA0368
Gene Name		sperm antigen with calponin homology and coiled-coil domains 1-like	KIAA0368
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Spindle Gap Junction Filamentous Actin	Proteasome Complex Nucleus Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane Cytoplasmic Membrane-bounded Vesicle ER To Golgi Transport Vesicle Endocytic Vesicle
	Molecular Function		Molecular_function
	Biological Process	Negative Regulation Of Microtubule Depolymerization Cell Cycle Cell Migration Actin Cytoskeleton Organization Negative Regulation Of Actin Filament Depolymerization Cell Division	ER-associated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APC GLIS2 KIAA0368 UBC UBE2I	28 interactors: AGTRAP ANK2 ANKRD17 CCDC57 CEP170B CKS1B CMTM5 CPD DNAJB9 DST FBXO2 GAREML GOLGB1 HNRNPM MKI67 MYH10 PCM1 PCYT1B RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483
Entrez ID		23384	23392
HPRD ID		11080	11078
Ensembl ID		ENSG00000100014	ENSG00000136813
Uniprot IDs		B2RMV2 Q69YQ0	J3KN16 Q5VYK3
PDB IDs
Enriched GO Terms of Interacting Partners?		Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Proteolysis Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Catabolic Process Positive Regulation Of SUMO Transferase Activity Mitotic Cell Cycle Process Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Canonical Wnt Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Wnt Signaling Pathway Mitotic Cell Cycle Checkpoint Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Cycle Process Negative Regulation Of Odontogenesis Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Signal Transduction Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Signal Transduction Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Transferase Activity Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle	ER-associated Ubiquitin-dependent Protein Catabolic Process Nucleus Localization Cell Cycle Establishment Of Nucleus Localization Cell Cycle Process Positive Regulation Of DNA Repair Cell Division Endomembrane System Organization Negative Regulation Of Muscle Cell Differentiation Histone H2A-K13 Ubiquitination Protein Localization To T-tubule Histone H2A-K15 Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of DNA Repair Histone H2A K63-linked Ubiquitination T-tubule Organization Protein Localization To M-band Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Response To DNA Damage Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process
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