NTMT1

Description		N-terminal Xaa-Pro-Lys N-methyltransferase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Methyltransferase Activity Protein Methyltransferase Activity Transferase Activity Histone Methyltransferase Activity N-terminal Protein N-methyltransferase Activity
	Biological Process	Chromatin Remodeling Spindle Organization Chromosome Segregation N-terminal Peptidyl-glycine Methylation N-terminal Peptidyl-proline Dimethylation Methylation N-terminal Peptidyl-serine Dimethylation N-terminal Peptidyl-serine Trimethylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: APP DDB2 DIS3 GLYR1 HNRNPD IKBKG RCC1
Entrez ID		28989
HPRD ID		10628
Ensembl ID		ENSG00000148335
Uniprot IDs		Q9BV86 S4R338
PDB IDs		2EX4 5CVD 5CVE 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 6DTN 6KDQ 6PVA 6PVB 6WH8 6WJ7 7K3D 7SS1 7U1M
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Catabolic Process Chromatin Binding Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Nucleosome Binding Protein-containing Complex Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium DNA Binding Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Heterodimerization Activity Chromatin Hepatocyte Dedifferentiation Cellular Response To Putrescine Acetylcholine Receptor Activator Activity Positive Regulation Of Gene Expression Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Positive Regulation Of Protein Import Nucleoplasm MRNA Destabilization RNA Destabilization Circadian Regulation Of Translation Nuclear MRNA Surveillance Of MRNA 3'-end Processing PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Nucleus Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of MRNA Catabolic Process Linear Polyubiquitin Binding Post-transcriptional Regulation Of Gene Expression Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Chromosome
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