SPINK7 and MT2A

Number of citations of the paper that reports this interaction (PMID 12646258)
4

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SPINK7	MT2A
Gene Name		serine peptidase inhibitor, Kazal type 7 (putative)	metallothionein 2A
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region	Nucleus Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Protein Binding Drug Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Cellular Copper Ion Homeostasis Cytokine-mediated Signaling Pathway Cellular Response To Drug Cellular Response To Interleukin-3 Cellular Response To Erythropoietin Negative Regulation Of Growth Interferon-gamma-mediated Signaling Pathway Cellular Response To Zinc Ion
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: EPB42 FTL HBA1 MRPS12 MT1G MT1H MT2A RABL6	13 interactors: ADAMTS4 ASS1 BARD1 CXorf40A DHODH ECT2 JMJD1C PAXIP1 PRKD1 RCHY1 SHBG SPINK7 USP25
Entrez ID		84651	4502
HPRD ID		16850	08863
Ensembl ID		ENSG00000145879
Uniprot IDs		P58062	P02795
PDB IDs		2LEO	1MHU 2MHU
Enriched GO Terms of Interacting Partners?		Cellular Response To Zinc Ion Response To Zinc Ion Cellular Response To Metal Ion Response To Inorganic Substance Cellular Response To Inorganic Substance Transition Metal Ion Homeostasis Cellular Response To Cadmium Ion Negative Regulation Of Growth Response To Metal Ion Response To Cadmium Ion Metal Ion Homeostasis Iron Ion Homeostasis Ion Homeostasis Regulation Of Growth Cellular Response To Erythropoietin Cellular Response To Interleukin-3 Cellular Response To Copper Ion Chemical Homeostasis Monocyte Activation Myeloid Cell Differentiation Erythrocyte Maturation Hemoglobin Metabolic Process Receptor-mediated Endocytosis Cellular Copper Ion Homeostasis Monocyte Differentiation Hydrogen Peroxide Catabolic Process Cellular Metal Ion Homeostasis Copper Ion Homeostasis Response To Copper Ion Oxygen Transport Homeostatic Process Cellular Cation Homeostasis Cellular Ion Homeostasis Bicarbonate Transport Hydrogen Peroxide Metabolic Process Cellular Chemical Homeostasis Cellular Response To Vascular Endothelial Growth Factor Stimulus Erythrocyte Development Peptide Cross-linking Spleen Development	Regulation Of Protein Metabolic Process Response To Stress Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Argininosuccinate Metabolic Process Positive Regulation Of Histone H3-K36 Methylation Primary Spermatocyte Growth Cellular Response To Stress Positive Regulation Of Histone Modification Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Protein Catabolic Process Protein Kinase D Signaling Negative Regulation Of MRNA 3'-end Processing Cellular Response To Amine Stimulus Response To Mycotoxin Positive Regulation Of Histone Deacetylase Activity 'de Novo' UMP Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Histone Modification Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Ubiquitination Response To Ionizing Radiation Regulation Of Metabolic Process Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Histone Deacetylase Activity Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Deacetylase Activity Positive Regulation Of Cell Death 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Negative Regulation Of Protein Export From Nucleus Response To Purine-containing Compound Positive Regulation Of Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Aspartate Metabolic Process Arginine Biosynthetic Process Protein K6-linked Ubiquitination Cellular Response To Laminar Fluid Shear Stress Cellular Response To Oleic Acid Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Chorion Development Positive Regulation Of Endothelial Cell Chemotaxis Cellular Response To Oxidative Stress Anatomical Structure Development Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization Regulation Of Nucleocytoplasmic Transport Diaphragm Development
Tagcloud ?			22rv1 bax beclin cflar cisplatin consequently create hif1alpha ic50 ions kappab1 kras mt1a mtt participate pc pnt1a prostatic regard resistance short summary survivin term tumorous verified zinc zip1 znt
Tagcloud (Difference) ?			22rv1 bax beclin cflar cisplatin consequently create hif1alpha ic50 ions kappab1 kras mt1a mtt participate pc pnt1a prostatic regard resistance short summary survivin term tumorous verified zinc zip1 znt
Tagcloud (Intersection) ?