SPINK7 and EPB42

Number of citations of the paper that reports this interaction (PMID 12970870)
1

Data Source:
HPRD (two hybrid)

		SPINK7	EPB42
Gene Name		serine peptidase inhibitor, Kazal type 7 (putative)	erythrocyte membrane protein band 4.2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Cytoskeleton Plasma Membrane Cortical Cytoskeleton
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding	Protein-glutamine Gamma-glutamyltransferase Activity Structural Constituent Of Cytoskeleton Protein Binding ATP Binding
	Biological Process	Negative Regulation Of Endopeptidase Activity	Cell Morphogenesis Regulation Of Cell Shape Peptide Cross-linking Hemoglobin Metabolic Process Erythrocyte Maturation Spleen Development Iron Ion Homeostasis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: EPB42 FTL HBA1 MRPS12 MT1G MT1H MT2A RABL6	13 interactors: ANK1 ANK2 BLOC1S4 CD47 DMTN EPB41 KRAS MAPK14 SLC4A1 SLC4A2 SPINK7 SPTAN1 STX12
Entrez ID		84651	2038
HPRD ID		16850	01517
Ensembl ID		ENSG00000145879	ENSG00000166947
Uniprot IDs		P58062	F5H563 P16452
PDB IDs		2LEO
Enriched GO Terms of Interacting Partners?		Cellular Response To Zinc Ion Response To Zinc Ion Cellular Response To Metal Ion Response To Inorganic Substance Cellular Response To Inorganic Substance Transition Metal Ion Homeostasis Cellular Response To Cadmium Ion Negative Regulation Of Growth Response To Metal Ion Response To Cadmium Ion Metal Ion Homeostasis Iron Ion Homeostasis Ion Homeostasis Regulation Of Growth Cellular Response To Erythropoietin Cellular Response To Interleukin-3 Cellular Response To Copper Ion Chemical Homeostasis Monocyte Activation Myeloid Cell Differentiation Erythrocyte Maturation Hemoglobin Metabolic Process Receptor-mediated Endocytosis Cellular Copper Ion Homeostasis Monocyte Differentiation Hydrogen Peroxide Catabolic Process Cellular Metal Ion Homeostasis Copper Ion Homeostasis Response To Copper Ion Oxygen Transport Homeostatic Process Cellular Cation Homeostasis Cellular Ion Homeostasis Bicarbonate Transport Hydrogen Peroxide Metabolic Process Cellular Chemical Homeostasis Cellular Response To Vascular Endothelial Growth Factor Stimulus Erythrocyte Development Peptide Cross-linking Spleen Development	Movement Of Cell Or Subcellular Component Chemotaxis Locomotion Axon Guidance Neuron Projection Development Blood Coagulation Hemostasis Neuron Development Bicarbonate Transport Axonogenesis Cell Morphogenesis Ion Homeostasis Axon Development Cell Development Regulation Of Body Fluid Levels Response To External Stimulus Neuron Differentiation Cell Morphogenesis Involved In Neuron Differentiation Protein Targeting To Plasma Membrane Wound Healing Erythrocyte Development Cell Projection Organization Regulation Of Intracellular PH Myeloid Cell Differentiation Regulation Of Cellular PH Neuron Projection Morphogenesis Actin Filament Capping Response To Wounding Cell Morphogenesis Involved In Differentiation Negative Regulation Of Actin Filament Depolymerization Homeostatic Process Organelle Organization P38MAPK Cascade Positive Regulation Of Platelet Aggregation Protein Localization To T-tubule Muscle Cell Differentiation Vesicle-mediated Transport Regulation Of PH Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Establishment Of Protein Localization To Plasma Membrane Cell Projection Morphogenesis Membrane Organization Cell Differentiation Chemical Homeostasis Cell Part Morphogenesis Generation Of Neurons Negative Regulation Of Protein Polymerization Protein Stabilization Protein Secretion By Platelet
Tagcloud ?			aplastic cbc cholelithiasis corpuscular crisis deformability dimax ektacytometry entails folic fragility hemolytic hemolyze hgb immunizations instituted mchc omin osmolality promptly repleted reticulocytes reticulocytosis sib sibs spherocytes spherocytosis splenectomy splenomegaly
Tagcloud (Difference) ?			aplastic cbc cholelithiasis corpuscular crisis deformability dimax ektacytometry entails folic fragility hemolytic hemolyze hgb immunizations instituted mchc omin osmolality promptly repleted reticulocytes reticulocytosis sib sibs spherocytes spherocytosis splenectomy splenomegaly
Tagcloud (Intersection) ?