SPINK7

Description		serine peptidase inhibitor Kazal type 7
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Inflammatory Response Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Experiencing mood swings ( 29500382)
Novel Interacting Genes		1 novel interacting genes: GALNT10
Interacting Genes		8 interacting genes: EPB42 FTL HBA1 MRPS12 MT1G MT1H MT2A RABL6
Entrez ID		84651
HPRD ID		16850
Ensembl ID		ENSG00000145879
Uniprot IDs		P58062
PDB IDs		2LEO
Enriched GO Terms of Interacting Partners?		Detoxification Of Copper Ion Cellular Response To Cadmium Ion Cellular Response To Zinc Ion Cellular Response To Copper Ion Intracellular Zinc Ion Homeostasis Response To Copper Ion Inorganic Ion Homeostasis Response To Cadmium Ion Response To Zinc Ion Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Chemical Homeostasis Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Cellular Response To Metal Ion Intracellular Chemical Homeostasis Negative Regulation Of Growth Cellular Homeostasis Homeostatic Process Response To Metal Ion Ferritin Complex Iron Ion Binding Haptoglobin Binding Cellular Response To Erythropoietin Nitric Oxide Transport Response To Erythropoietin Regulation Of Growth Ankyrin-1 Complex Protein-glutamine Gamma-glutamyltransferase Activity Ferric Iron Binding Cellular Response To Interleukin-3 Metal Ion Binding Monocyte Activation Hemoglobin Metabolic Process Haptoglobin-hemoglobin Complex Autolysosome Hemoglobin Complex Oxygen Carrier Activity Polypeptide N-acetylgalactosaminyltransferase Activity Carbon Dioxide Transport Intracellular Copper Ion Homeostasis Oxygen Transport Erythrocyte Maturation Hydrogen Peroxide Catabolic Process Endocytic Vesicle Lumen Monocyte Differentiation Copper Ion Homeostasis Ferrous Iron Binding Multicellular Organismal-level Iron Ion Homeostasis One-carbon Compound Transport
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