PARD6B and ZSCAN4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PARD6B	ZSCAN4
Description		par-6 family cell polarity regulator beta	zinc finger and SCAN domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Membrane Apical Plasma Membrane Cell Junction Protein-containing Complex Apical Part Of Cell Extracellular Exosome Tight Junction Anchoring Junction PAR Polarity Complex	Chromosome, Telomeric Region Nucleus Chromosome
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell-cell Junction Assembly Centrosome Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell Division Regulation Of Cellular Localization Protein-containing Complex Assembly	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Recombination
Pathways		Tight junction interactions RHOV GTPase cycle	Zygotic genome activation (ZGA)
Drugs
Diseases
GWAS		Bipolar disorder ( 21771265)
Interacting Genes		34 interacting genes: APP ARAP3 BANP CDC42 CDCA4 CEP76 FRMD6 GMCL1 GOLGA2 HSF2BP HTRA1 MAGOHB OGT PALS1 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RASSF3 RHOJ RHOQ SIAH1 TCP10L3 TRIB3 TRIM35 WDR83 YWHAB YWHAH YWHAZ ZSCAN4	13 interacting genes: CIB3 CTBP2 EXOC8 FAM110A HAT1 HCK KAT5 LAMTOR3 PARD6B SMAD1 SMAD9 TBC1D22B TRAF3
Entrez ID		84612	201516
HPRD ID		18703	15899
Ensembl ID		ENSG00000124171	ENSG00000180532
Uniprot IDs		Q9BYG5	Q8NAM6
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Cell Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity PAR Polarity Complex Establishment Of Cell Polarity Bicellular Tight Junction Apical Junction Complex Tight Junction GBD Domain Binding Cytoplasm Diacylglycerol-dependent Serine/threonine Kinase Activity GTP-dependent Protein Binding Cytoskeleton Organization Intracellular Protein Localization Response To Insulin Cell-cell Junction Organization Protein Kinase Binding Cell Cortex Response To Peptide Hormone Supramolecular Fiber Organization Cellular Response To Insulin Stimulus Regulation Of Synaptic Plasticity Phosphoserine Residue Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Apical Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Identical Protein Binding Intracellular Signal Transduction Establishment Of Golgi Localization Negative Regulation Of Protein Localization To Nucleus Actin Filament Organization Thioesterase Binding Establishment Of Centrosome Localization Organelle Organization Schmidt-Lanterman Incisure Plasma Membrane Cell Junction Organization Asymmetric Cell Division Regulation Of Synapse Organization Regulation Of Protein Localization Golgi Localization Regulation Of Cell Communication Extracellular Exosome Regulation Of Signaling Regulation Of Protein Localization To Membrane Regulation Of Programmed Cell Death Cellular Response To Peptide Hormone Stimulus Regulation Of Insulin Receptor Signaling Pathway Regulation Of D-glucose Transmembrane Transport Cellular Localization	Heteromeric SMAD Protein Complex SMAD Protein Complex Histone H4 Acetyltransferase Activity I-SMAD Binding SMAD Protein Signal Transduction Protein-lysine-acetyltransferase Activity Innate Immune Response-activating Signaling Pathway Histone Acetyltransferase Activity Protein Acetylation Activation Of Innate Immune Response Transcription Regulator Complex Histone H2AK5 Acetyltransferase Activity
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