CMKLR1 and TPST1

Number of citations of the paper that reports this interaction (PMID 17558413)
13

Data Source:
HPRD (in vitro)

		CMKLR1	TPST1
Gene Name		chemokine-like receptor 1	tyrosylprotein sulfotransferase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Golgi Membrane Membrane Integral Component Of Membrane
	Molecular Function	Receptor Activity G-protein Coupled Receptor Activity Chemokine Receptor Activity Protein Binding	Protein-tyrosine Sulfotransferase Activity
	Biological Process	Skeletal System Development Chemotaxis Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Macrophage Chemotaxis Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-12 Production Positive Regulation Of Fat Cell Differentiation Regulation Of Calcium-mediated Signaling Chemokine-mediated Signaling Pathway	Peptidyl-tyrosine Sulfation Inflammatory Response
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 22688191) Erectile dysfunction and prostate cancer treatment ( 20932654) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 21483023)
Protein-Protein Interactions		2 interactors: TPST1 TPST2	6 interactors: CCR1 CCR8 CMKLR1 GP1BA GPR1 SELPLG
Entrez ID		1240	8460
HPRD ID		03829	07216
Ensembl ID		ENSG00000174600	ENSG00000169902
Uniprot IDs		Q99788	O60507
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Sulfation Protein Sulfation Sulfation Sulfur Compound Metabolic Process Prevention Of Polyspermy Fusion Of Sperm To Egg Plasma Membrane Plasma Membrane Fusion Egg Activation Peptidyl-amino Acid Modification Membrane Fusion Single Fertilization Fertilization Cellular Protein Modification Process	Chemokine-mediated Signaling Pathway G-protein Coupled Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine Cell Adhesion Locomotion Positive Regulation Of Leukocyte Chemotaxis Cytokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Migration Cell Surface Receptor Signaling Pathway Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Behavior Response To Wounding Cellular Response To Stimulus Leukocyte Adhesive Activation Regulation Of Chemotaxis Cellular Response To Organic Substance G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Immune System Process Regulation Of Behavior Leukocyte Migration Response To Organic Substance Response To Stimulus Positive Regulation Of Macrophage Chemotaxis Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Signal Transduction Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Migration Immune Response Positive Regulation Of Cell Motility Thrombin Receptor Signaling Pathway Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Leukocyte Tethering Or Rolling Regulation Of Macrophage Chemotaxis Regulation Of Monocyte Chemotaxis Dendritic Cell Chemotaxis Signaling Cell Communication Blood Coagulation, Intrinsic Pathway Cellular Metal Ion Homeostasis Blood Coagulation Hemostasis Cellular Cation Homeostasis Negative Regulation Of Interleukin-12 Production
Tagcloud ?		12q24 appendix array broad chemokine chromosome cloning encodes encoding fetal fluorescence formyl hematopoietic homology hybridization localized lymph marrow node notable nucleotide sequence seven situ spleen structural thymus transmembrane
Tagcloud (Difference) ?		12q24 appendix array broad chemokine chromosome cloning encodes encoding fetal fluorescence formyl hematopoietic homology hybridization localized lymph marrow node notable nucleotide sequence seven situ spleen structural thymus transmembrane
Tagcloud (Intersection) ?