CMKLR1 and TPST2

Number of citations of the paper that reports this interaction (PMID 17558413)
13

Data Source:
HPRD (in vitro)

		CMKLR1	TPST2
Gene Name		chemokine-like receptor 1	tyrosylprotein sulfotransferase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity G-protein Coupled Receptor Activity Chemokine Receptor Activity Protein Binding	Protein-tyrosine Sulfotransferase Activity
	Biological Process	Skeletal System Development Chemotaxis Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Macrophage Chemotaxis Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-12 Production Positive Regulation Of Fat Cell Differentiation Regulation Of Calcium-mediated Signaling Chemokine-mediated Signaling Pathway	Peptidyl-tyrosine Sulfation Fusion Of Sperm To Egg Plasma Membrane Prevention Of Polyspermy
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 22688191) Erectile dysfunction and prostate cancer treatment ( 20932654) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 21483023)
Protein-Protein Interactions		2 interactors: TPST1 TPST2	5 interactors: CCR1 CCR8 CMKLR1 GPR1 SELPLG
Entrez ID		1240	8459
HPRD ID		03829	07217
Ensembl ID		ENSG00000174600	ENSG00000128294
Uniprot IDs		Q99788	O60704
PDB IDs			3AP1 3AP2 3AP3
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Sulfation Protein Sulfation Sulfation Sulfur Compound Metabolic Process Prevention Of Polyspermy Fusion Of Sperm To Egg Plasma Membrane Plasma Membrane Fusion Egg Activation Peptidyl-amino Acid Modification Membrane Fusion Single Fertilization Fertilization Cellular Protein Modification Process	Chemokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine G-protein Coupled Receptor Signaling Pathway Locomotion Cytokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Leukocyte Migration Chemotaxis Cellular Response To Organic Substance Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Behavior Immune System Process Regulation Of Chemotaxis G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Leukocyte Adhesive Activation Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Response To Organic Substance Regulation Of Behavior Leukocyte Migration Cell Adhesion Cell Surface Receptor Signaling Pathway Immune Response Cellular Calcium Ion Homeostasis Positive Regulation Of Macrophage Chemotaxis Calcium Ion Homeostasis Cellular Response To Stimulus Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Positive Regulation Of Monocyte Chemotaxis Leukocyte Tethering Or Rolling Cellular Metal Ion Homeostasis Regulation Of Macrophage Chemotaxis Regulation Of Monocyte Chemotaxis Dendritic Cell Chemotaxis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Response To External Stimulus Negative Regulation Of Interleukin-12 Production Negative Regulation Of Bone Mineralization Negative Regulation Of Biomineral Tissue Development Cellular Chemical Homeostasis Response To Stimulus Dendritic Cell Migration Ion Homeostasis
Tagcloud ?		12q24 appendix array broad chemokine chromosome cloning encodes encoding fetal fluorescence formyl hematopoietic homology hybridization localized lymph marrow node notable nucleotide sequence seven situ spleen structural thymus transmembrane	ameliorates backcross catalyzes ch chr chrs congenic d2mit255 d2mit304 d2mit62 dw dwarfism genetical grt hypoplasia hyporesponsiveness hypothyroidism indispensable linkage organogenesis progenies qtl qtls sulfation sulfotransferase svjcl ter thyroid tyrosylprotein
Tagcloud (Difference) ?		12q24 appendix array broad chemokine chromosome cloning encodes encoding fetal fluorescence formyl hematopoietic homology hybridization localized lymph marrow node notable nucleotide sequence seven situ spleen structural thymus transmembrane	ameliorates backcross catalyzes ch chr chrs congenic d2mit255 d2mit304 d2mit62 dw dwarfism genetical grt hypoplasia hyporesponsiveness hypothyroidism indispensable linkage organogenesis progenies qtl qtls sulfation sulfotransferase svjcl ter thyroid tyrosylprotein
Tagcloud (Intersection) ?