CUL4B and SALL2

Number of citations of the paper that reports this interaction (PMID 21228219)
4

Data Source:
BioGRID (pull down)

		CUL4B	SALL2
Gene Name		cullin 4B	spalt-like transcription factor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Cul4B-RING E3 Ubiquitin Ligase Complex Extracellular Vesicular Exosome	NuRD Complex
	Molecular Function	Damaged DNA Binding Protein Binding Ubiquitin Protein Ligase Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Histone H2A Monoubiquitination Positive Regulation Of Protein Catabolic Process UV-damage Excision Repair Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle	Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Development Transcription, DNA-templated Neural Tube Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AHR APP AR CAND1 COMMD1 DCUN1D1 DCUN1D3 DCUN1D4 DCUN1D5 DDB1 DDB2 DTL ESR1 KPNA2 KPNA4 KPNB1 NEDD8 RBX1 RNF7 SALL2 SIN3A UBC	8 interactors: ADAMTSL4 CEP76 CUL4A CUL4B DDB1 EWSR1 RBBP7 ZMIZ2
Entrez ID		8450	6297
HPRD ID		02251	03743
Ensembl ID		ENSG00000158290	ENSG00000165821
Uniprot IDs		Q13620	E7EW59 Q9Y467
PDB IDs		2DO7 4A0C 4A0L 4A64
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Monoubiquitination Protein Neddylation Protein Ubiquitination Intracellular Receptor Signaling Pathway NLS-bearing Protein Import Into Nucleus Regulation Of Transcription From RNA Polymerase II Promoter DNA Metabolic Process Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Response To UV Cellular Macromolecule Catabolic Process Response To Light Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly UV-damage Excision Repair Positive Regulation Of Transcription From RNA Polymerase II Promoter Prostate Gland Development Response To Abiotic Stimulus Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Response To Radiation Regulation Of Cell Cycle Phase Transition Histone H2A Monoubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Modification-dependent Protein Catabolic Process Cellular Response To Stimulus Histone H2A Ubiquitination Cellular Nitrogen Compound Metabolic Process Positive Regulation Of DNA-templated Transcription, Initiation Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Protein Catabolic Process Nucleotide-excision Repair, DNA Damage Removal Cellular Response To Organic Substance Rhythmic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Import Into Nucleus Histone Monoubiquitination DNA Repair Nuclear Import Regulation Of DNA-templated Transcription, Initiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Catabolic Process Copper Ion Homeostasis Regulation Of Apoptotic Process	UV-damage Excision Repair Histone H2A Monoubiquitination Histone H2A Ubiquitination Regulation Of Cell Cycle Process Histone Monoubiquitination Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Histone Ubiquitination Protein Monoubiquitination Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Cellular Response To UV DNA Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Nucleotide-excision Repair Cellular Response To Light Stimulus Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Heat Acclimation Positive Regulation Of Mitotic Cell Cycle Cellular Protein Catabolic Process Protein Ubiquitination DNA Repair Chromatin Modification Protein Modification By Small Protein Conjugation Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Catabolic Process Response To UV Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Stress Cellular Response To Radiation Proteolysis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Organization Cellular Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Granulocyte Differentiation Nitrogen Compound Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process
Tagcloud ?		absent alleviate assemble augmented blunted dampening depleted downregulated drives driving e3 ectopic exacerbate feedback greatly h2o2 ligases loop mildly negatively nhfs oxidative proteosomal replicative ros senescence senescent stressed ubiquitination	adding ap4 bioinformatic deregulated deregulation doxorubicin electrophoretic embryo evidences genotoxic half hydroxy knockin mefs necessarily neurotrophin p53er r175h r248w r249s radiosensitive repress repressed represses spalt tam tamoxifen unable wt1
Tagcloud (Difference) ?		absent alleviate assemble augmented blunted dampening depleted downregulated drives driving e3 ectopic exacerbate feedback greatly h2o2 ligases loop mildly negatively nhfs oxidative proteosomal replicative ros senescence senescent stressed ubiquitination	adding ap4 bioinformatic deregulated deregulation doxorubicin electrophoretic embryo evidences genotoxic half hydroxy knockin mefs necessarily neurotrophin p53er r175h r248w r249s radiosensitive repress repressed represses spalt tam tamoxifen unable wt1
Tagcloud (Intersection) ?