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DGCR14 and LYST
Number of citations of the paper that reports this interaction (PMID
11984006
)
18
Data Source:
BioGRID
(two hybrid)
HPRD
(in vitro, two hybrid)
DGCR14
LYST
Gene Name
DiGeorge syndrome critical region gene 14
lysosomal trafficking regulator
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Catalytic Step 2 Spliceosome
Cytosol
Endomembrane System
Microtubule Cytoskeleton
Extrinsic Component Of Membrane
Molecular Function
Molecular_function
Protein Binding
Protein Binding
Phospholipid Binding
Biological Process
MRNA Splicing, Via Spliceosome
Nervous System Development
Neutrophil Mediated Immunity
T Cell Mediated Immunity
Phospholipid Metabolic Process
Microtubule-based Process
Lysosome Organization
Blood Coagulation
Leukocyte Chemotaxis
Melanosome Organization
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
Positive Regulation Of Natural Killer Cell Activation
Secretion Of Lysosomal Enzymes
Mast Cell Secretory Granule Organization
Natural Killer Cell Mediated Cytotoxicity
Response To Drug
Defense Response To Bacterium
Defense Response To Protozoan
Pigmentation
Defense Response To Virus
Phospholipid Homeostasis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
11 interactors:
CDK5RAP3
CRP
DHX16
FRA10AC1
GNB2L1
LYST
PFDN1
RBM4
TTC14
VIM
WNK2
24 interactors:
ATN1
CALM1
CELF4
CENPJ
CNTROB
CSNK2B
DGCR14
DNAJC14
EFS
ESRRA
HGS
HNRNPM
KPNB1
MED12
MRPL17
MRPS31
NCDN
PCBP4
TNNI3
VTA1
YWHAB
YWHAQ
YWHAZ
ZNF521
Entrez ID
8220
1130
HPRD ID
03452
06060
Ensembl ID
ENSG00000100056
ENSG00000143669
Uniprot IDs
Q96DF8
Q99698
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Translation
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
Positive Regulation Of CAMP Catabolic Process
Mast Cell Secretory Granule Organization
Regulation Of Neuron Differentiation
Negative Regulation Of Hydrogen Peroxide-induced Neuron Death
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Regulation Of Ion Homeostasis
Regulation Of Cell Differentiation
IRES-dependent Translational Initiation
Cap-independent Translational Initiation
Regulation Of Neurogenesis
Endosome Transport Via Multivesicular Body Sorting Pathway
Circadian Regulation Of Translation
Defense Response To Bacterium
Negative Regulation Of Oxidative Stress-induced Neuron Death
Bergmann Glial Cell Differentiation
Negative Regulation Of Vasodilation
Secretion Of Lysosomal Enzymes
Protein Ufmylation
Negative Regulation Of Translation In Response To Stress
Regulation Of Cell Development
Negative Regulation Of Translation Involved In Gene Silencing By MiRNA
Positive Regulation Of Superoxide Anion Generation
Positive Regulation Of Protein Homooligomerization
Positive Regulation Of Gastrulation
Phospholipid Homeostasis
Regulation Of Gene Expression
Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Cytoplasmic Translational Initiation
Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Positive Regulation Of Mitochondrial Depolarization
Opsonization
Leukocyte Mediated Immunity
Adaptive Immune Response
Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Phagocytosis
Regulation Of Translation
Cell Differentiation
Central Nervous System Development
Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Regulation Of Superoxide Anion Generation
Regulation Of Interleukin-8 Secretion
Regulation Of Cellular Localization
Rhythmic Process
Regulation Of Metabolic Process
Cytoplasmic Translation
Positive Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Translation In Response To Stress
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrion Organization
Mitochondrion Organization
Protein Targeting
Alternative MRNA Splicing, Via Spliceosome
Regulation Of Mitochondrion Organization
Centriole Replication
Membrane Organization
Gene Expression
Protein Transport
Centriole Assembly
Establishment Of Protein Localization
Epidermal Growth Factor Receptor Signaling Pathway
Multicellular Organismal Development
Centrosome Duplication
ERBB Signaling Pathway
Positive Regulation Of Transport
Substantia Nigra Development
Regulation Of Intracellular Transport
Intrinsic Apoptotic Signaling Pathway
Nervous System Development
Positive Regulation Of Apoptotic Signaling Pathway
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Neural Nucleus Development
Intracellular Protein Transport
Centrosome Cycle
Protein Localization
Positive Regulation Of Intracellular Transport
Apoptotic Process
Establishment Of Localization In Cell
Developmental Process
Mitochondrial Translational Elongation
Mitochondrial Translational Initiation
Mitochondrial Translational Termination
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Programmed Cell Death
Intracellular Transport
Regulation Of Cellular Localization
Cell Death
Death
Anatomical Structure Development
Mitochondrial Translation
System Development
Midbrain Development
Golgi Reassembly
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
RNA Splicing
Tagcloud
?
ataxin
atp13a2
atxn3
b12
cag
cgg
chediak
coexist
cytopathies
fmr1
fragile
gaucher
gba
glucocerebrosidase
hereditary
higashi
idiopathic
joseph
kufor
levodopa
machado
park2
parkin
parkinsonism
pn
polg1
premutation
rakeb
tremor
Tagcloud (Difference)
?
ataxin
atp13a2
atxn3
b12
cag
cgg
chediak
coexist
cytopathies
fmr1
fragile
gaucher
gba
glucocerebrosidase
hereditary
higashi
idiopathic
joseph
kufor
levodopa
machado
park2
parkin
parkinsonism
pn
polg1
premutation
rakeb
tremor
Tagcloud (Intersection)
?