TRIM39 and RNF166

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		TRIM39	RNF166
Gene Name		tripartite motif containing 39	ring finger protein 166
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity Identical Protein Binding	Zinc Ion Binding
	Biological Process	Apoptotic Process Protein Ubiquitination Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		52 interactors: APP CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 KDM1A LNX1 LXN MED18 MNAT1 OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMD9 RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1 UBTD2 UBXN1 UBXN6 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26	16 interactors: MKRN3 RNF41 TRIM39 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U UBE2W UBE2Z USP2
Entrez ID		56658	115992
HPRD ID		09298	15260
Ensembl ID		ENSG00000204599	ENSG00000158717
Uniprot IDs		Q9HCM9	Q96A37
PDB IDs		2DID 2DIF 2ECJ
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Cellular Protein Metabolic Process Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Metabolic Process Regulation Of Proteolysis Regulation Of Protein Ubiquitination Protein K63-linked Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition Toll-like Receptor 4 Signaling Pathway Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Toll-like Receptor Signaling Pathway Regulation Of Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Activation Of Innate Immune Response	Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Protein Modification Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Metabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K63-linked Ubiquitination Cellular Metabolic Process Protein Monoubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress ISG15-protein Conjugation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Cellular Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Protein Ubiquitination Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Negative Regulation Of Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Protein Catabolic Process Activation Of Innate Immune Response Regulation Of Mitotic Cell Cycle Metabolic Process Positive Regulation Of Innate Immune Response Mitotic Spindle Assembly Checkpoint Histone Ubiquitination Spindle Assembly Checkpoint Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stress Regulation Of Protein Ubiquitination
Tagcloud ?		293t aeromonas aggregate b30 bloodthirsty btr18 btr20 btr21 btr22 danio deduced e3 gill hydrophila intestine ligase mentioned multigene nj rbcc remarkably rerio tripartite ubch6 ubiquitin ubiquitylated ubiquitylation zebrafish
Tagcloud (Difference) ?		293t aeromonas aggregate b30 bloodthirsty btr18 btr20 btr21 btr22 danio deduced e3 gill hydrophila intestine ligase mentioned multigene nj rbcc remarkably rerio tripartite ubch6 ubiquitin ubiquitylated ubiquitylation zebrafish
Tagcloud (Intersection) ?