ELOF1 and CHMP6

Number of citations: 0 (PubMedID 16730941)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		ELOF1	CHMP6
Name		elongation factor 1	charged multivesicular body protein 6
Structure
GO Annotations	Cellular Component	Nucleus Chromosome Transcription Elongation Factor Complex	Autophagosome Membrane Kinetochore ESCRT III Complex Nuclear Pore Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Endosome Membrane Endomembrane System Membrane Midbody Late Endosome Membrane Multivesicular Body Membrane Extracellular Exosome Amphisome Membrane
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Protein-macromolecule Adaptor Activity	Protein Binding Protein-containing Complex Binding
	Biological Process	DNA Repair Transcription-coupled Nucleotide-excision Repair Transcription Elongation By RNA Polymerase II DNA Damage Response	Plasma Membrane Repair Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Transport Macroautophagy Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Regulation Of Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport Regulation Of Exosomal Secretion ESCRT III Complex Assembly
Pathways		None	Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		8 interacting genes: ATP5F1C C5orf22 CHMP6 JUN KDM1A MAPK6 SMURF1 SUV39H1	8 interacting genes: CHMP4A CHMP4B ELOF1 METTL9 SNCA SNF8 VPS25 VPS36
Entrez ID		84337	79643
HPRD ID		14639	08564
Ensembl ID		ENSG00000130165	ENSG00000176108
Uniprot IDs		P60002	Q96FZ7
PDB IDs		8B3D 9ER2 9FD2	2K3W 3HTU
GO Terms Enriched among Interactors		None	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Organization Multivesicular Body Assembly Late Endosome To Vacuole Transport Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Multivesicular Body Sorting Pathway ESCRT II Complex Endosome Organization Membrane Organization Macroautophagy Vacuolar Transport Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Endosomal Transport Protein Localization To Vacuole Autophagy Vesicle Organization Establishment Of Protein Localization To Organelle Late Endosome Membrane Establishment Of Protein Localization To Vacuole Vesicle-mediated Transport Protein Homodimerization Activity Organelle Assembly ESCRT III Complex Amphisome Membrane Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Fusion With Vacuole Nucleus Organization Multivesicular Body-lysosome Fusion Lipid Binding Endosome Viral Budding From Plasma Membrane Lysosomal Membrane Organization Cellular Component Assembly Establishment Of Localization In Cell Organelle Organization Late Endosome To Lysosome Transport Kinetochore Microtubule Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Midbody Abscission Regulation Of Microtubule Cytoskeleton Organization Viral Budding Nuclear Membrane Reassembly Intracellular Protein Localization Mitotic Cytokinetic Process Protein Transport Plasma Membrane Repair Multivesicular Body Membrane Protein Targeting To ER