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POLDIP3 and POLD2
Number of citations of the paper that reports this interaction (PMID
12522211
)
17
Data Source:
HPRD
(two hybrid)
POLDIP3
POLD2
Gene Name
polymerase (DNA-directed), delta interacting protein 3
polymerase (DNA directed), delta 2, accessory subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Transcription Export Complex
Nucleoplasm
Cytoplasm
Nuclear Speck
Exon-exon Junction Complex
Intracellular Membrane-bounded Organelle
Nucleus
Nucleoplasm
Molecular Function
Nucleotide Binding
Protein Binding
Poly(A) RNA Binding
DNA Binding
DNA-directed DNA Polymerase Activity
Protein Binding
Biological Process
Poly(A)+ MRNA Export From Nucleus
Positive Regulation Of Translation
Mitotic Cell Cycle
Telomere Maintenance Via Recombination
Telomere Maintenance
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
Telomere Maintenance Via Semi-conservative Replication
DNA Biosynthetic Process
Pathways
Nucleotide Excision Repair
Gap-filling DNA repair synthesis and ligation in TC-NER
Extension of Telomeres
Repair synthesis for gap-filling by DNA polymerase in TC-NER
Leading Strand Synthesis
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
DNA strand elongation
Mismatch Repair
Polymerase switching
Telomere Maintenance
Removal of DNA patch containing abasic residue
Resolution of Abasic Sites (AP sites)
Removal of the Flap Intermediate from the C-strand
Base Excision Repair
Polymerase switching on the C-strand of the telomere
Synthesis of DNA
Chromosome Maintenance
Lagging Strand Synthesis
Processive synthesis on the C-strand of the telomere
Processive synthesis on the lagging strand
S Phase
Telomere C-strand (Lagging Strand) Synthesis
Repair synthesis of patch ~27-30 bases long by DNA polymerase
Cell Cycle, Mitotic
Gap-filling DNA repair synthesis and ligation in GG-NER
Removal of the Flap Intermediate
Global Genomic NER (GG-NER)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
Transcription-coupled NER (TC-NER)
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
BANP
ERH
GOLGA2
KRT40
LZTS2
MTUS2
PNMA1
POLD2
RPS6KA1
RPS6KB1
16 interactors:
CCHCR1
CDK2
CDKN1A
EP300
KCTD13
LSM6
PCNA
POLD1
POLD3
POLD4
POLDIP2
POLDIP3
SOX12
WRN
WRNIP1
XRN1
Entrez ID
84271
5425
HPRD ID
17875
15982
Ensembl ID
ENSG00000100227
ENSG00000106628
Uniprot IDs
B4E0L0
Q659C6
Q9BY77
A4D2J4
B2R5S4
P49005
PDB IDs
3E0J
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Mitotic Cell Cycle
Positive Regulation Of Hepatic Stellate Cell Activation
Positive Regulation Of Skeletal Muscle Tissue Growth
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
DNA Replication
DNA Biosynthetic Process
DNA Synthesis Involved In DNA Repair
Nucleotide-excision Repair, DNA Gap Filling
Base-excision Repair
Telomere Maintenance Via Semi-conservative Replication
Cellular Response To DNA Damage Stimulus
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Telomere Maintenance
Mitotic Recombination
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Telomere Maintenance Via Telomere Lengthening
DNA-dependent DNA Replication
Transcription-coupled Nucleotide-excision Repair
DNA Repair
Mismatch Repair
Chromosome Organization
Cellular Response To Stress
DNA Metabolic Process
Mitotic Cell Cycle
DNA Recombination
Nucleotide-excision Repair
Regulation Of DNA Replication
Nucleobase-containing Compound Metabolic Process
Cell Cycle Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Organelle Organization
Regulation Of DNA-dependent DNA Replication Initiation
Cell Cycle
Response To Stress
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Macromolecule Biosynthetic Process
Signal Transduction By P53 Class Mediator
G2/M Transition Of Mitotic Cell Cycle
Response To UV
Positive Regulation Of DNA Metabolic Process
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Mitochondrion Morphogenesis
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
G1/S Transition Of Mitotic Cell Cycle
Cellular Macromolecule Catabolic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Biosynthetic Process
Tagcloud
?
a2
als
altogether
amyotrophic
becomes
cytoplasm
degeneration
dimerization
dysregulation
escaping
frontotemporal
ftld
heterogeneous
hnrnp
hnrnps
knocking
lateral
lobar
localizes
neurotoxic
neurotoxicity
normally
ribonucleoprotein
sclerosis
shifts
splicing
tdp
transactive
u
Tagcloud (Difference)
?
a2
als
altogether
amyotrophic
becomes
cytoplasm
degeneration
dimerization
dysregulation
escaping
frontotemporal
ftld
heterogeneous
hnrnp
hnrnps
knocking
lateral
lobar
localizes
neurotoxic
neurotoxicity
normally
ribonucleoprotein
sclerosis
shifts
splicing
tdp
transactive
u
Tagcloud (Intersection)
?