POLDIP3 and ZRANB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		POLDIP3	ZRANB1
Description		DNA polymerase delta interacting protein 3	zinc finger RANBP2-type containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Cytoplasmic Ribonucleoprotein Granule	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein-containing Complex Binding	Catalytic Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Hydrolase Activity Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Deubiquitinase Activity
	Biological Process	Regulation Of Translation Poly(A)+ MRNA Export From Nucleus Positive Regulation Of Translation MRNA Transport	Autophagosome Assembly Proteolysis Cytoskeleton Organization Wnt Signaling Pathway Cell Migration Protein Deubiquitination Regulation Of Cell Morphogenesis Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Phosphatidylinositol Phosphate Biosynthetic Process Protein K63-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Deubiquitination
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	Degradation of beta-catenin by the destruction complex Ovarian tumor domain proteases
Drugs
Diseases
GWAS			Blood urea nitrogen levels ( 31152163) Creatine kinase levels ( 29403010) Height ( 25429064 31562340) Lung cancer ( 34062886)
Interacting Genes		32 interacting genes: BANP BICD2 CCNDBP1 CEBPA ERH EXOSC8 GOLGA2 GTPBP3 HMBOX1 HOMEZ HSF2BP KRT31 KRT40 LZTS2 MID2 MTUS2 OGT OSGIN1 OTX2 PIBF1 PNMA1 POLD2 POLR1C RAD51D RBPMS RPS6KA1 RPS6KB1 SBK3 SNRPF SRPK2 TEKT4 ZRANB1	130 interacting genes: AKT1 ARHGEF5 ARRDC2 ARRDC3 ATOSB BAHD1 BRD1 C1orf35 CARD9 CBX7 CBX8 CCDC120 CCDC13 CCDC185 CCDC187 CCHCR1 CCNL1 CDC45 CDK18 CDKL3 CNNM3 CORO7 CPNE7 CWF19L2 DCX DNAJB13 DTNB DUSP13B ENKD1 FAIM FAM124B FAM161A FAM161B FAM50B FAM90A1 FNDC11 GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 HOXB5 HOXC8 IL16 INO80B IP6K3 IQUB JRK KANK2 KIF9 KIFC3 LENG1 LMO3 LNX1 MAGEB4 MAGOH MCRS1 METTL21A MID2 MPPED1 MYEF2 NEK6 NUDT16L1 PHF1 PHF19 PKN1 PLEKHN1 PNMA5 POLDIP3 POLL PPP1R18 PSPC1 RAPGEF3 RASAL3 SCNM1 SDCBP SLC7A11 SNCA STAMBPL1 SUV39H1 SYT17 SYTL4 TBC1D3 TBC1D30 TBC1D3B TBC1D3C TBC1D3G TBC1D3K TCEANC THAP7 TIE1 TLE5 TNS4 TRAF3IP3 TRAF4 TRAF6 TRAPPC2 TRAPPC2B TSGA10IP TSPYL4 TSTD2 TTC23 TWIST1 UBASH3A UBC UBE2D1 UBE2G1 USP2 UVRAG VAV3 WT1 ZBTB24 ZBTB47 ZNF124 ZNF17 ZNF250 ZNF408 ZNF417 ZNF438 ZNF490 ZNF497 ZNF552 ZNF575 ZNF587 ZNF599 ZNF648 ZNF764 ZNF775 ZNF792 ZNF837
Entrez ID		84271	54764
HPRD ID		17875	11738
Ensembl ID		ENSG00000100227	ENSG00000019995
Uniprot IDs		B4E0L0 F6VRR5 Q9BY77	Q9UGI0
PDB IDs			3ZRH 5AF6
Enriched GO Terms of Interacting Partners?		Organelle Organization Nucleus Nucleoplasm Methylosome Cytoskeleton TORC1 Signaling	Protein Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Zinc Ion Binding Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Nuclear Speck Regulation Of Macromolecule Metabolic Process Microtubule Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process
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