SPATC1L and FOXN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPATC1L	FOXN1
Description		spermatogenesis and centriole associated 1 like	forkhead box N1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Sperm Head-tail Coupling Apparatus	Chromatin Nucleus
	Molecular Function	Protein Binding Protein Kinase A Regulatory Subunit Binding Identical Protein Binding	Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Spermatogenesis Actin Polymerization Or Depolymerization Positive Regulation Of CAMP/PKA Signal Transduction	Hair Follicle Development Lymphocyte Homeostasis T Cell Lineage Commitment Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Defense Response Epidermis Development Animal Organ Morphogenesis Regulation Of Gene Expression Hemopoiesis Cell Differentiation Keratinocyte Differentiation Positive Regulation Of Epithelial Cell Differentiation Regulation Of T Cell Differentiation In Thymus Nail Development T Cell Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Blood Vessel Morphogenesis Thymus Development Positive Regulation Of Hair Follicle Development Lymphoid Lineage Cell Migration Into Thymus Thymus Epithelium Morphogenesis Regulation Of Positive Thymic T Cell Selection
Pathways
Drugs
Diseases			T-B+Severe combined immunodeficiencies (SCIDs), including the following eight diseases: X-linked SCID; Janus kinase-3 (Jak3) deficiency; IL-7 receptor alpha (IL7R alpha) deficiency; IL-2 receptor alpha (IL2R alpha) deficiency; CD45 deficiency; CD3 deficiency; Winged Helix Nude (WHN) deficiency; Immunodeficiency with thynoma
GWAS			Bone mineral density ( 31790847) Metabolite levels ( 31628463) Tonsillectomy ( 27182965 28928442)
Interacting Genes		51 interacting genes: ACOT7 ARL4A ARMC7 ATPAF2 CABP2 CLTC DISC1 EXOSC8 FOXN1 FSD2 GOLGA6A GTF3C6 HOOK2 IKZF1 KIFC3 KRT40 KRTAP5-9 LZTS2 MISP MTUS2 MYO15B NCK2 NUTF2 NXF1 PARN PHC2 PHF11 PIAS2 PICK1 PINK1 PLEC PNMA1 POLR1C PPP1CB PPP1CC QARS1 RAD51D RBMY1F RBMY1J REL SIAH1 SNRNP70 SYCE1 TCF4 TEKT4 TRIM27 TRMO TSR2 UBL5 ZBTB4 ZBTB8B	13 interacting genes: CDA CDC23 DMRT3 HOXA1 LHX8 MAPKBP1 OTUD3 PIN1 SPATC1L TLE5 TRAF2 TRAPPC6A TSSK1B
Entrez ID		84221	8456
HPRD ID		10753	02907
Ensembl ID		ENSG00000160284	ENSG00000109101
Uniprot IDs		Q9H0A9	O15353
PDB IDs			5OCN 6EL8
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoskeleton Identical Protein Binding Nucleus RNA Metabolic Process PTW/PP1 Phosphatase Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?