FOXN1

Description		forkhead box N1
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GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Hair Follicle Development Lymphocyte Homeostasis T Cell Lineage Commitment Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Defense Response Epidermis Development Animal Organ Morphogenesis Regulation Of Gene Expression Hemopoiesis Cell Differentiation Keratinocyte Differentiation Positive Regulation Of Epithelial Cell Differentiation Regulation Of T Cell Differentiation In Thymus Nail Development T Cell Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Blood Vessel Morphogenesis Thymus Development Positive Regulation Of Hair Follicle Development Lymphoid Lineage Cell Migration Into Thymus Thymus Epithelium Morphogenesis Regulation Of Positive Thymic T Cell Selection
Pathways
Drugs
Diseases		T-B+Severe combined immunodeficiencies (SCIDs), including the following eight diseases: X-linked SCID; Janus kinase-3 (Jak3) deficiency; IL-7 receptor alpha (IL7R alpha) deficiency; IL-2 receptor alpha (IL2R alpha) deficiency; CD45 deficiency; CD3 deficiency; Winged Helix Nude (WHN) deficiency; Immunodeficiency with thynoma
GWAS		Bone mineral density ( 31790847) Metabolite levels ( 31628463) Tonsillectomy ( 27182965 28928442)
Interacting Genes		13 interacting genes: CDA CDC23 DMRT3 HOXA1 LHX8 MAPKBP1 OTUD3 PIN1 SPATC1L TLE5 TRAF2 TRAPPC6A TSSK1B
Entrez ID		8456
HPRD ID		02907
Ensembl ID		ENSG00000109101
Uniprot IDs		O15353
PDB IDs		5OCN 6EL8
Enriched GO Terms of Interacting Partners?
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