BFSP2 and MBIP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		BFSP2	MBIP
Description		beaded filament structural protein 2	MAP3K12 binding inhibitory protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Intermediate Filament Plasma Membrane Cell Cortex Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Mitotic Spindle ATAC Complex
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	Cytoskeleton Organization Visual Perception Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization Cell Maturation Lens Fiber Cell Development	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Embryonic Development Positive Regulation Of JNK Cascade Regulation Of Cell Division Regulation Of Cell Cycle
Pathways			HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS			Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335 32769997)
Interacting Genes		56 interacting genes: ABI3 AMOTL2 ANKRD33 ATF4 BEX3 BEX5 BFSP1 BICRAL BLOC1S2 C3orf62 CAGE1 CALCOCO1 CCDC183 CDCA4 CDR2L CEP44 CEP63 COPS6 CT55 DISC1 DMAP1 DRC12 ECSIT HAUS1 HGS KRT14 KRT24 KRT27 KRT31 KRT37 MAGEA6 MBIP MCCD1 MYOG OIP5 PBX2 PBX4 POU6F2 PPP1R13B PSMC5 RINT1 RNASE10 SAPCD2 SCOC SERTAD3 SNAPC5 SNAPIN SUFU SYCE1 SYCE1L TRIB3 USHBP1 USP54 WASHC3 ZNF343 ZNF620	47 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR1 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SHANK3 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TSC1 TXLNA TXLNB VPS28 VTA1 WDR5
Entrez ID		8419	51562
HPRD ID		04444	14368
Ensembl ID		ENSG00000170819	ENSG00000151332
Uniprot IDs		Q13515	B2RCV0 Q9NS73
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Structural Molecule Activity Protein Binding Organelle Organization Regulation Of Lysosome Size BORC Complex Vesicle Transport Along Microtubule	Positive Regulation Of Long-term Neuronal Synaptic Plasticity Protein Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Nuclear Pore Localization Endosome Organization Positive Regulation Of GTPase Activity Cytoplasm Organelle Organization Positive Regulation Of Hydrolase Activity
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