BFSP2 and KRT37

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BFSP2	KRT37
Description		beaded filament structural protein 2	keratin 37
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Intermediate Filament Plasma Membrane Cell Cortex Membrane	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Structural Constituent Of Eye Lens Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Cytoskeleton Organization Visual Perception Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization Cell Maturation Lens Fiber Cell Development	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS			Squamous cell lung carcinoma ( 28604730)
Interacting Genes		56 interacting genes: ABI3 AMOTL2 ANKRD33 ATF4 BEX3 BEX5 BFSP1 BICRAL BLOC1S2 C3orf62 CAGE1 CALCOCO1 CCDC183 CDCA4 CDR2L CEP44 CEP63 COPS6 CT55 DISC1 DMAP1 DRC12 ECSIT HAUS1 HGS KRT14 KRT24 KRT27 KRT31 KRT37 MAGEA6 MBIP MCCD1 MYOG OIP5 PBX2 PBX4 POU6F2 PPP1R13B PSMC5 RINT1 RNASE10 SAPCD2 SCOC SERTAD3 SNAPC5 SNAPIN SUFU SYCE1 SYCE1L TRIB3 USHBP1 USP54 WASHC3 ZNF343 ZNF620	47 interacting genes: AGXT AQP1 BCAS2 BFSP2 C21orf58 CCDC196 CLCNKA COL8A1 DES FAM110A FBXW5 GNG13 HAPLN2 HGS HOXA1 HSF4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT83 KRT85 KRT86 MTG1 NUFIP2 OIP5 OTX1 PIN1 PKN1 PSMA1 SMARCD1 SMARCE1 TBC1D21 TXLNB USHBP1
Entrez ID		8419	8688
HPRD ID		04444	05175
Ensembl ID		ENSG00000170819	ENSG00000108417
Uniprot IDs		Q13515	O76014
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Structural Molecule Activity Protein Binding Organelle Organization Regulation Of Lysosome Size BORC Complex Vesicle Transport Along Microtubule	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratinization Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Epidermis Development Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Cytosol Developmental Process Cornified Envelope Brahma Complex NpBAF Complex Tissue Development RSC-type Complex NBAF Complex Protein Binding Peptide Cross-linking
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