MBIP and KAT14

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)
HPRD (two hybrid)

		MBIP	KAT14
Description		MAP3K12 binding inhibitory protein 1	lysine acetyltransferase 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Mitotic Spindle ATAC Complex	Nucleus Nucleoplasm Cytoplasm Mitotic Spindle ATAC Complex
	Molecular Function	Protein Kinase Inhibitor Activity Protein Binding Identical Protein Binding	Histone Acetyltransferase Activity Protein Binding Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups LIM Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Embryonic Development Positive Regulation Of JNK Cascade Regulation Of Cell Division Regulation Of Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes	HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Hypertension ( 31513605) Thyroid cancer ( 22267200) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 25743335 32769997)	Thyroglobulin plasma levels ( 30929638)
Interacting Genes		47 interacting genes: BFSP2 CALM1 CCDC85B CCNC CEP63 COPS4 DGCR6 DGCR6L DIP2A DRC7 EPB41L3 EXOC8 FXR1 FXR2 ING5 KAT14 KLC3 LIMS1 LMNB1 LMO2 LMO3 MAP3K12 MAPK6 MCM7 MIS18A MOAP1 MYD88 NDEL1 NINL PIK3R3 PLEKHF2 POLR1C PPFIA1 RAP1GDS1 RAPGEF1 SHANK3 SMARCB1 STX11 TGIF2LY TRIM55 TRIM63 TSC1 TXLNA TXLNB VPS28 VTA1 WDR5	11 interacting genes: ACTC1 CEP70 CSRP2 DPPA4 H3C1 H4C1 H4C16 MBIP TRIM27 TRIM54 ZFY
Entrez ID		51562	57325
HPRD ID		14368	16765
Ensembl ID		ENSG00000151332	ENSG00000149474
Uniprot IDs		B2RCV0 Q9NS73	A0A075B6H4 Q9H8E8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Long-term Neuronal Synaptic Plasticity Protein Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Regulation Of Long-term Neuronal Synaptic Plasticity Nuclear Pore Localization Endosome Organization Positive Regulation Of GTPase Activity Cytoplasm Organelle Organization Positive Regulation Of Hydrolase Activity	Nucleosome Telomere Organization Nucleosome Assembly Nucleosome Organization Structural Constituent Of Chromatin CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Protein-DNA Complex Assembly Protein Localization To Chromosome, Centromeric Region Regulation Of Megakaryocyte Differentiation Protein Localization To Chromatin Chromatin Remodeling Protein Heterodimerization Activity Chromosome Organization Chromatin Organization Negative Regulation Of Myeloid Cell Differentiation Protein Localization To Chromosome Actomyosin Structure Organization Organelle Organization Cytoplasmic Actin-based Contraction Involved In Cell Motility Mesenchyme Migration Z Disc
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