FHIP1B and AGTRAP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FHIP1B	AGTRAP
Description		FHF complex subunit HOOK interacting protein 1B	angiotensin II receptor associated protein
Image			No pdb structure
GO Annotations	Cellular Component	FHF Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Cortex Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Angiotensin Type II Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport Protein Localization To Perinuclear Region Of Cytoplasm	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway
Pathways			Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS			Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Basophil percentage of white cells ( 32888494) Systolic blood pressure ( 19430483)
Interacting Genes		9 interacting genes: AGTRAP AKTIP HOOK1 HOOK2 RAB5B RABAC1 REEP6 RTN1 RTN3	138 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 ANKS6 AP3M1 APOA4 AQP6 ARAF ARFIP2 ARHGAP1 ATP5F1E BCL2L13 BPIFA2 CAPNS1 CCDC70 CD160 CD79A CELA3A CIAO2A COQ8A CPLX1 CPLX4 CRCT1 CYB5R3 CYBC1 DDA1 DDX55 DGCR6 DIABLO DNAJC1 ECPAS ERGIC3 ETFRF1 FAM114A1 FAM209A FARS2 FASTKD3 FATE1 FFAR2 FGA FHIP1B FNDC9 GABARAPL2 GAD1 GAD2 GDNF GPR152 GPX8 GTF2H1 GTF3C1 H4C7 HARS2 HIBADH HMGB1 HSBP1L1 HSCB HSD17B13 HSFX1 HSFX2 HSPA4 IL7R ISCU KCNK5 KIR2DL3 KIR3DL3 LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MGST3 MIEF1 MIEF2 MMD MRM1 MRPL11 MRRF MTERF3 MUTYH MYG1 NDRG4 NDUFAF3 NFU1 NFYB NKG7 PBX3 PCTP PCYT1A PDHX PIMREG PITPNC1 PNPO POLDIP2 PPIF PRPF18 PTPN9 RAB30 RACK1 RBFA RETREG3 RMDN2 S100B SCAND1 SENP2 SH3GLB1 SLC18A1 SLC7A14 SMG9 SNX1 SPG21 SSX3 SSX5 STAG3L1 STAR STARD4 STMN4 STX1A SUCLA2 SYT16 TBRG4 TCEA2 TCEANC2 TFAM THAP4 TMEM139 TMEM14B TMEM31 TMPPE TPD52L3 TTPA TUBA1B TXN2 UBE2I YARS2 ZFYVE21 ZNF391
Entrez ID		84067	57085
HPRD ID		08002	16379
Ensembl ID		ENSG00000051009	ENSG00000177674
Uniprot IDs		Q8N612	Q6RW13
PDB IDs		8QAT
Enriched GO Terms of Interacting Partners?		FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm HOPS Complex Endosome Organization Early Endosome To Late Endosome Transport Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Formation Lysosome Organization Endosome To Lysosome Transport Endosomal Transport Endoplasmic Reticulum Tubular Network Membrane Organization Vesicle Organization Endoplasmic Reticulum Membrane Organization Lysosomal Transport Organelle Organization Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Amyloid-beta Formation Vacuolar Transport Negative Regulation Of Amyloid Precursor Protein Catabolic Process Vacuole Organization Dynein Light Intermediate Chain Binding Vesicle-mediated Transport Regulation Of Amyloid-beta Formation Golgi Apparatus Regulation Of Amyloid Precursor Protein Catabolic Process Cytoplasmic Microtubule Organization Regulation Of Amide Metabolic Process Endoplasmic Reticulum Membrane Protein Transport Intracellular Transport Angiotensin Type II Receptor Activity Establishment Of Protein Localization Golgi Membrane Manchette Assembly Cytoskeleton-dependent Intracellular Transport Cellular Localization Plasma Membrane To Endosome Transport Endoplasmic Reticulum Positive Regulation Of Protein Binding Establishment Of Localization In Cell Brain Development Postsynaptic Density Microtubule Binding Cytoplasmic Vesicle Intracellular Protein Localization Identical Protein Binding Proline-rich Region Binding Ubiquitin-like Protein Transferase Activity GTP-dependent Protein Binding Angiotensin-activated Signaling Pathway	Mitochondrial Matrix Mitochondrion Protein Binding Lipid Binding Succinate Metabolic Process Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity
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