FHIP1B and REEP6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		FHIP1B	REEP6
Description		FHF complex subunit HOOK interacting protein 1B	receptor accessory protein 6
Image			No pdb structure
GO Annotations	Cellular Component	FHF Complex	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport Protein Localization To Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception
Pathways
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: AGTRAP AKTIP HOOK1 HOOK2 RAB5B RABAC1 REEP6 RTN1 RTN3	46 interacting genes: AQP6 ARL6IP1 ATP5PF BIK CD79A CDC37 CERT1 COQ8A CYB561 CYB5R3 EBAG9 FHIP1B GJA8 GORASP2 GPR152 HMBOX1 HSD17B13 KRTAP3-1 LEPROTL1 LITAF LMNA LNX1 MIEF2 NDRG4 NTAQ1 PICK1 PTPN9 RPS20 SDCBP SLC30A8 SNX1 SNX11 SNX15 SNX8 SPG21 STING1 SYT16 TIMMDC1 TLCD4 TMED8 TMEM143 TMPPE TNS2 TXN2 WIPI2 ZFYVE21
Entrez ID		84067	92840
HPRD ID		08002	16629
Ensembl ID		ENSG00000051009	ENSG00000115255
Uniprot IDs		Q8N612	A0A1L5BXV2 Q96HR9
PDB IDs		8QAT
Enriched GO Terms of Interacting Partners?		FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm HOPS Complex Endosome Organization Early Endosome To Late Endosome Transport Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Formation Lysosome Organization Endosome To Lysosome Transport Endosomal Transport Endoplasmic Reticulum Tubular Network Membrane Organization Vesicle Organization Endoplasmic Reticulum Membrane Organization Lysosomal Transport Organelle Organization Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Amyloid-beta Formation Vacuolar Transport Negative Regulation Of Amyloid Precursor Protein Catabolic Process Vacuole Organization Dynein Light Intermediate Chain Binding Vesicle-mediated Transport Regulation Of Amyloid-beta Formation Golgi Apparatus Regulation Of Amyloid Precursor Protein Catabolic Process Cytoplasmic Microtubule Organization Regulation Of Amide Metabolic Process Endoplasmic Reticulum Membrane Protein Transport Intracellular Transport Angiotensin Type II Receptor Activity Establishment Of Protein Localization Golgi Membrane Manchette Assembly Cytoskeleton-dependent Intracellular Transport Cellular Localization Plasma Membrane To Endosome Transport Endoplasmic Reticulum Positive Regulation Of Protein Binding Establishment Of Localization In Cell Brain Development Postsynaptic Density Microtubule Binding Cytoplasmic Vesicle Intracellular Protein Localization Identical Protein Binding Proline-rich Region Binding Ubiquitin-like Protein Transferase Activity GTP-dependent Protein Binding Angiotensin-activated Signaling Pathway	Lipid Binding Establishment Of Protein Localization Identical Protein Binding Membrane
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