NCALD and ANOS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NCALD	ANOS1
Description		neurocalcin delta	anosmin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Clathrin Coat Of Trans-Golgi Network Vesicle	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Membrane Extracellular Matrix
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Tubulin Binding Clathrin Binding Alpha-tubulin Binding Metal Ion Binding	Serine-type Endopeptidase Inhibitor Activity Extracellular Matrix Structural Constituent Protein Binding Heparin Binding Peptidase Inhibitor Activity
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Regulation Of Signal Transduction Vesicle-mediated Transport Calcium-mediated Signaling	Chemotaxis Cell Adhesion Axon Guidance Neuron Differentiation
Pathways		Activation of Ca-permeable Kainate Receptor	FGFR1c ligand binding and activation Negative regulation of FGFR1 signaling
Drugs
Diseases			Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Age-related hearing impairment ( 24939585) Cerebral amyloid angiopathy ( 25188341) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Coffee consumption ( 21876539) Cognitive performance ( 20125193) Coronary artery disease ( 33020668) Gait speed in old age ( 28077804) LDL peak particle diameter (total fat intake interaction) ( 26112879) Medication use (beta blocking agents) ( 31015401) Microalbuminuria ( 26631737) Perceived sweetness of sucrose ( 31005972) Red cell distribution width ( 32888494) Systolic blood pressure ( 30224653)	Estimated glomerular filtration rate ( 31015462)
Interacting Genes		33 interacting genes: ACTB ANOS1 APOL3 C19orf44 C1QTNF2 CLTC CREM DTX2 FGF6 FZD7 GOLGA7 GPX7 IGFBP6 KRT6A LCE2D LIF LITAF LY6G6D MEOX2 MICOS10-NBL1 MIEF2 MLLT10 MYDGF NBL1 PLAAT2 PNP SBSN SPRED1 SRGN TMEM14B TPSG1 TUBA4A TUBB	6 interacting genes: FGFR2 FGFR3 FN1 NCALD SDC2 UBQLN1
Entrez ID		83988	3730
HPRD ID		09466	02393
Ensembl ID		ENSG00000104490	ENSG00000011201
Uniprot IDs		B2RB70 P61601	P23352
PDB IDs			1ZLG
Enriched GO Terms of Interacting Partners?		Extracellular Region Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Structural Constituent Of Cytoskeleton Determination Of Dorsal Identity Morphogen Activity Negative Regulation Of Monocyte Chemotaxis Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction Maintenance Of Protein Location Extracellular Space Protein Binding Maintenance Of Location	Positive Regulation Of Phospholipase Activity Fibroblast Growth Factor Receptor Activity Positive Regulation Of Lipase Activity Endochondral Bone Growth Bone Growth Fibroblast Growth Factor Binding Bone Morphogenesis Identical Protein Binding Regulation Of ERK1 And ERK2 Cascade Regulation Of Developmental Growth Organ Growth Transmembrane Receptor Protein Tyrosine Kinase Activity Bone Mineralization Fibroblast Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Involved In Negative Regulation Of Apoptotic Process In Bone Marrow Cell Fibroblast Growth Factor Receptor Signaling Pathway Involved In Positive Regulation Of Cell Proliferation In Bone Marrow Fibroblast Growth Factor Receptor Signaling Pathway Involved In Hemopoiesis Negative Regulation Of Store-operated Calcium Channel Activity Biomineral Tissue Development Regulation Of Signal Transduction Regulation Of Growth Positive Regulation Of Hydrolase Activity Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Bone Maturation Regulation Of Protein Modification Process Regulation Of MAPK Cascade Cell Surface Protein Tyrosine Kinase Activity Mesenchymal Cell Differentiation Involved In Lung Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Mammary Gland Specification Ventricular Zone Neuroblast Division Cellular Response To Decreased Oxygen Levels Prostate Epithelial Cord Elongation Cellular Response To Hypoxia Orbitofrontal Cortex Development Mammary Gland Bud Formation Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development Branch Elongation Involved In Salivary Gland Morphogenesis Negative Regulation Of Monocyte Activation Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Heparin Binding Cellular Response To Oxygen Levels Positive Regulation Of Developmental Growth Calcium-independent Cell-matrix Adhesion Regulation Of Cell Communication Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Signaling Prostate Gland Morphogenesis
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