NCALD and DTX2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		NCALD	DTX2
Gene Name		neurocalcin delta	deltex 2, E3 ubiquitin ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytosol Clathrin Coat Of Trans-Golgi Network Vesicle Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Actin Binding Calcium Ion Binding Tubulin Binding Clathrin Binding Alpha-tubulin Binding	Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Synaptic Transmission Vesicle-mediated Transport Calcium-mediated Signaling	Notch Signaling Pathway Protein Ubiquitination
Pathways		Activation of Kainate Receptors upon glutamate binding Activation of Ca-permeable Kainate Receptor Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ionotropic activity of Kainate Receptors Transmission across Chemical Synapses	Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS		Coffee consumption ( 21876539) Cognitive performance ( 20125193)
Protein-Protein Interactions		8 interactors: ACTB C1QTNF2 CLTC DTX2 MEOX2 PNP TUBA4A TUBB	41 interactors: ABHD16A ALKBH4 ARNT2 C1orf94 DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS RBPMS RFX6 RHOXF2 RIMBP3 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1
Entrez ID		83988	113878
HPRD ID		09466	16841
Ensembl ID		ENSG00000104490	ENSG00000091073
Uniprot IDs		B2RB70 P61601	Q86UW9
PDB IDs
Enriched GO Terms of Interacting Partners?		'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Inosine Catabolic Process NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Nicotinamide Riboside Catabolic Process Protein Polymerization Interleukin-2 Secretion Urate Biosynthetic Process G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Carbohydrate Metabolic Process Mitotic Cell Cycle Process Mitotic Cell Cycle Platelet Activation Somite Specification Cellular Component Assembly Establishment Of Localization In Cell Interleukin-2 Production Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Immune System Process Protein Complex Assembly Cell Cycle Process Protein Heterotrimerization Urate Metabolic Process Protein Folding Purine Ribonucleoside Catabolic Process Positive Regulation Of Glycogen Biosynthetic Process Cellular Localization Cellular Protein Complex Assembly Segment Specification Positive Regulation Of Fatty Acid Oxidation	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K48-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transcription, DNA-templated RNA Biosynthetic Process Protein Modification By Small Protein Conjugation Transcription From RNA Polymerase II Promoter Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Innate Immune Response Protein K11-linked Ubiquitination RNA Metabolic Process Cellular Response To Oxygen Levels Heart Trabecula Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Hypoxia Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Notch Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Cellular Response To Stimulus Cellular Nitrogen Compound Metabolic Process Pancreatic Epsilon Cell Differentiation Glutaminyl-tRNA Aminoacylation Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Pancreatic D Cell Differentiation Cleavage Furrow Ingression Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Protein Polyubiquitination Glandular Epithelial Cell Differentiation Signal Transduction Trabecula Morphogenesis Positive Regulation Of Innate Immune Response Vesicle Fusion Regulation Of Immune System Process Prolyl-tRNA Aminoacylation Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Histamine Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?		8q22 antiepileptic autistic disability dysmorphic encompassed epilepsy epileptic girl intellectual iq kuechler lips neurocalcin overlapping proposita q22 recognizable refined ribonucleotide rrm2b seizure sentences smallest spoke telecanthus vermilion walked word	algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Difference) ?		8q22 antiepileptic autistic disability dysmorphic encompassed epilepsy epileptic girl intellectual iq kuechler lips neurocalcin overlapping proposita q22 recognizable refined ribonucleotide rrm2b seizure sentences smallest spoke telecanthus vermilion walked word	algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Intersection) ?