PIP4K2B and HMBOX1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PIP4K2B	HMBOX1
Gene Name		phosphatidylinositol-5-phosphate 4-kinase, type II, beta	homeobox containing 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Receptor Signaling Protein Activity ATP Binding 1-phosphatidylinositol-4-phosphate 5-kinase Activity 1-phosphatidylinositol-5-phosphate 4-kinase Activity	DNA Binding Protein Binding
	Biological Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Cell Surface Receptor Signaling Pathway Intracellular Signal Transduction Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Synthesis of PIPs at the plasma membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS		Height ( 20881960)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: BTK HMBOX1 TNFRSF1A UBQLN4	48 interactors: AEBP2 APP ASB7 ATP5O BYSL C20orf195 C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM206A FAM74A4 FARS2 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587
Entrez ID		8396	79618
HPRD ID		04463	07964
Ensembl ID		ENSG00000141720	ENSG00000147421
Uniprot IDs		P78356	D3DSU2 Q6NT76
PDB IDs		1BO1	2CUF 4J19
Enriched GO Terms of Interacting Partners?		Regulation Of B Cell Cytokine Production Cellular Response To Molecule Of Fungal Origin	Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Chromatin Organization Biosynthetic Process Chromatin Modification Cellular Metabolic Process Regulation Of Energy Homeostasis Positive Regulation Of Glycolytic Process Chromosome Organization Fatty Acid Homeostasis Histone Modification Histone-serine Phosphorylation Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Cholesterol Metabolic Process Organelle Organization Sterol Metabolic Process Negative Regulation Of TOR Signaling Cholesterol Biosynthetic Process Translational Termination Positive Regulation Of Autophagy Neuron Recognition Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Synaptic Target Recognition Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Double-strand Break Repair Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Histone Phosphorylation Sterol Biosynthetic Process Protein Ubiquitination Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Anion Homeostasis Translational Elongation Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Cellular Process Regulation Of RNA Metabolic Process Cerebellum Structural Organization
Tagcloud ?		accompanied amplification bearing cancers dramatic encoding express homozygous importantly kinases knocking lethality littermates phosphate phosphatidylinositol plastic preventing ros senescence subset synthetic tp53 treating viable xenografts	adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 scnn1b scnn1g vasopressin
Tagcloud (Difference) ?		accompanied amplification bearing cancers dramatic encoding express homozygous importantly kinases knocking lethality littermates phosphate phosphatidylinositol plastic preventing ros senescence subset synthetic tp53 treating viable xenografts	adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 scnn1b scnn1g vasopressin
Tagcloud (Intersection) ?