HMBOX1 and MRPL28

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HMBOX1	MRPL28
Gene Name		homeobox containing 1	mitochondrial ribosomal protein L28
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome
	Molecular Function	DNA Binding Protein Binding	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Translation Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		48 interactors: AEBP2 APP ASB7 ATP5O BYSL C20orf195 C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM206A FAM74A4 FARS2 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587	12 interactors: APP BANP CDR2 FAM9B HMBOX1 HTR2A IKZF3 OXA1L TEF TRAF3IP2 TRAF4 TUBB3
Entrez ID		79618	10573
HPRD ID		07964	06889
Ensembl ID		ENSG00000147421	ENSG00000086504
Uniprot IDs		D3DSU2 Q6NT76	Q13084
PDB IDs		2CUF 4J19
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Chromatin Organization Biosynthetic Process Chromatin Modification Cellular Metabolic Process Regulation Of Energy Homeostasis Positive Regulation Of Glycolytic Process Chromosome Organization Fatty Acid Homeostasis Histone Modification Histone-serine Phosphorylation Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Cholesterol Metabolic Process Organelle Organization Sterol Metabolic Process Negative Regulation Of TOR Signaling Cholesterol Biosynthetic Process Translational Termination Positive Regulation Of Autophagy Neuron Recognition Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Synaptic Target Recognition Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Double-strand Break Repair Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Histone Phosphorylation Sterol Biosynthetic Process Protein Ubiquitination Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Anion Homeostasis Translational Elongation Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Cellular Process Regulation Of RNA Metabolic Process Cerebellum Structural Organization	Cell Death Death Phospholipase C-activating Serotonin Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Mitochondrial Proton-transporting ATP Synthase Complex Assembly Collateral Sprouting In Absence Of Injury Proton-transporting ATP Synthase Complex Assembly Positive Regulation Of Phosphatidylinositol Biosynthetic Process Regulation Of Protein Binding Cellular Localization Collateral Sprouting Axon Midline Choice Point Recognition Adult Behavior Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Immunoglobulin Secretion Positive Regulation Of Phospholipid Biosynthetic Process Axon Choice Point Recognition Regulation Of Protein Kinase Activity Positive Regulation Of Cellular Biosynthetic Process Artery Smooth Muscle Contraction Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of ATPase Activity Tonic Smooth Muscle Contraction B Cell Apoptotic Process Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Neuron Remodeling Positive Regulation Of Protein Homodimerization Activity Urinary Bladder Smooth Muscle Contraction Regulation Of Binding Learning Or Memory Positive Regulation Of Glycolytic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Protein Localization Serotonin Receptor Signaling Pathway Vascular Smooth Muscle Contraction Behavioral Response To Cocaine RNA Metabolic Process Cognition Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Respiratory Chain Complex I Biogenesis Negative Regulation Of Synaptic Transmission, Glutamatergic Apoptotic Process Cellular Calcium Ion Homeostasis Sleep Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Calcium Ion Homeostasis Programmed Cell Death
Tagcloud ?		adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 scnn1b scnn1g vasopressin	asexual candida cerevisiae chromosome cluster coding contains else equivalent exclude fourth gcn3 glabrata his3 homologues includes kb mating mfa1 pathogenic rearrangement saccharomyces section sequenced somewhere stp1 tfb3 xi xv
Tagcloud (Difference) ?		adherens aqp2 aqp3 bioinformatic collecting crebbp ctnnb1 duct elf3 enacbeta enacgamma esbl flanking gatad2b gov helixweb http hypotheses isotope junb junctions mnpd mpkccd nih pser552 rangap1 scnn1b scnn1g vasopressin	asexual candida cerevisiae chromosome cluster coding contains else equivalent exclude fourth gcn3 glabrata his3 homologues includes kb mating mfa1 pathogenic rearrangement saccharomyces section sequenced somewhere stp1 tfb3 xi xv
Tagcloud (Intersection) ?