HMBOX1 and SFR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		HMBOX1	SFR1
Description		homeobox containing 1	SWI5 dependent homologous recombination repair protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body	Nucleus Nucleoplasm Nucleolus Centrosome Swi5-Sfr1 Complex
	Molecular Function	DNA Binding Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomerase Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Telomere-telomerase Complex Assembly	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Positive Regulation Of DNA-templated Transcription Cellular Response To Estrogen Stimulus
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		98 interacting genes: ABITRAM AEBP2 ANKRD36 APP ATP5PO BAZ2B BEND7 BRD1 BYSL C8orf33 CARD9 CBX8 CCDC187 CCNG1 CDC7 CDCA8 CDK18 DAB1 DNTTIP1 DYNLL1 ENKD1 ENTPD2 FAM13C FAM161A FAM217B FAM74A4 FAM90A1 FARS2 FGF11 FNDC11 FRMD6 FXR2 GAS2L2 GNL3L GSC2 INO80B IPO13 KAT5 KIF9 LMO1 LMO3 LNX1 MAGEH1 MCRS1 MEOX1 MEOX2 MFAP1 MORF4L1 MORF4L2 MRPL11 MRPL28 PAX5 PAX6 PIAS2 PICK1 PIP4K2B PKD1P1 POLDIP3 POLL PRKAA1 PRKAA2 PRPF18 RBMY2FP RCOR3 REEP6 RPL9 RPS25 SAP30L SCNM1 SDCBP SFR1 SH2D4A SNRPB2 SNW1 SYT6 TBP TCEA2 TCEANC TSGA10IP TUFM U2AF2 UBA6 UBE2I UBE2Z VAX1 VPS72 WT1 ZBTB24 ZBTB26 ZFYVE26 ZMAT2 ZMYM5 ZNF250 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688	14 interacting genes: CDC5L CEP70 DTNBP1 EXOC1 FBXO7 HMBOX1 MRFAP1L1 NDC80 NMI RAD51 RINT1 SWI5 TFIP11 TRAF3IP1
Entrez ID		79618	119392
HPRD ID		07964	12590
Ensembl ID		ENSG00000147421	ENSG00000156384
Uniprot IDs		Q6NT76	Q86XK3
PDB IDs		2CUF 4J19
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear Speck Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Lipid Droplet Disassembly Protein Binding Positive Regulation Of DNA Repair NuA4 Histone Acetyltransferase Complex Regulation Of Macromolecule Biosynthetic Process Phosphatidylethanolamine Biosynthetic Process DNA Binding Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Nucleic Acid Metabolic Process Regulation Of Macromolecule Metabolic Process DNA Recombination Chromatin Organization Spliceosomal Complex Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To Glucose Starvation Protein Localization To Lipid Droplet Positive Regulation Of DNA Metabolic Process Phosphatidylcholine Biosynthetic Process Positive Regulation Of Glycolytic Process Somite Specification Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of DNA Repair Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Phosphatidylethanolamine Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Metabolic Process Regulation Of Tubulin Deacetylation Astrocyte Differentiation	Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Process Telomere Maintenance Negative Regulation Of Interferon-beta Production Negative Regulation Of Cell Cycle Chromosome Organization Centrosome Telomere Organization DNA Metabolic Process Regulation Of Cell Cycle Process Identical Protein Binding DNA Damage Response Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Cell Cycle Phase Transition Chromosome, Telomeric Region Cytoplasm Response To Glucoside Negative Regulation Of Type I Interferon Production Kinetochore Adaptor Activity Negative Regulation Of Mitotic Cell Cycle Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Telomere-telomerase Complex Assembly Regulation Of Interferon-beta Production Regulation Of Cell Cycle Cilium Assembly Response To Stress Meiosis I Cell Cycle Process Mitotic Recombination-dependent Replication Fork Processing DNA Strand Exchange Activity Cellular Response To Ionizing Radiation Presynaptic Intermediate Filament Cytoskeleton G2/MI Transition Of Meiotic Cell Cycle Spliceosomal Complex Disassembly Cilium Organization Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Swi5-Sfr1 Complex Organelle Organization Negative Regulation Of Cellular Component Organization Catalytic Step 2 Spliceosome Nuclear Division Positive Regulation Of Protein K48-linked Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition Organelle Assembly U2-type Post-mRNA Release Spliceosomal Complex Lewy Body Core Dsl1/NZR Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?