KRTAP9-3 and RAMP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP9-3	RAMP3
Description		keratin associated protein 9-3	receptor activity modifying protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Lysosome Plasma Membrane Cell Surface Membrane Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex
	Molecular Function	Protein Binding Identical Protein Binding	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity
	Biological Process		Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of CAMP/PKA Signal Transduction Amylin Receptor 3 Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Adrenomedullin Receptor Signaling Pathway
Pathways		Keratinization	G alpha (s) signalling events Calcitonin-like ligand receptors
Drugs			Pramlintide
Diseases
GWAS			Hepatic lipid content in extreme obesity ( 25246029)
Interacting Genes		135 interacting genes: ADAMTSL4 ALPP ANKS1A ATN1 CARD10 CATSPER1 CCER1 CELF5 CERCAM CHRD CHRNG CNNM3 COL8A1 CRCT1 CREB5 CRH CYSRT1 DCDC2 DMRT3 DOCK2 ECM1 FAM124B FBXO34 FBXW5 GET4 GLRX3 GNE HOXA1 HOXA9 INCA1 ITGB4 JOSD1 KLHL38 KLK8 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LMNTD2 LNX1 MAPKBP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NPDC1 NR1D2 NR4A3 NTM NUFIP2 OTX1 PAX5 PAX6 PGAP6 PHLDA1 POU4F2 PRKAB2 PTPMT1 PVR RAMP3 RGS20 SH3GLB2 SHFL SLC13A5 SLC23A1 SLC25A18 SMCP SPMIP6 SPRY1 TFAP2D TOX3 TRIM42 TSPAN4 UNC119 VASN VGLL3 WNT11 YY1 ZDHHC1 ZNF414 ZNF439 ZNF440 ZNF497 ZNF575	15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1
Entrez ID		83900	10268
HPRD ID		13950	05517
Ensembl ID		ENSG00000204873	ENSG00000122679
Uniprot IDs		Q9BYQ3	A4D2L1 O60896
PDB IDs			6UUS 6UVA 7TZF 8F0K 8F2A 8F2B
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Protein Binding Tissue Development Hair Cycle	Intermediate Filament Calcitonin Receptor Activity Calcitonin Gene-related Peptide Receptor Activity Calcitonin Gene-related Peptide Receptor Signaling Pathway Calcitonin Family Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Amylin Receptor Complex 2 Calcitonin Family Receptor Activity Transmembrane Signaling Receptor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Amylin Receptor Complex 1 Calcitonin Binding Regulation Of Copper Ion Transmembrane Transport G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cellular Response To Sucrose Stimulus Amylin Receptor Complex 3 Extracellular Exosome Biogenesis Adrenomedullin Binding CGRP Receptor Complex Amylin Receptor 3 Signaling Pathway Amylin Receptor Activity SNARE Complex Disassembly Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Proteinase Activated Receptor Binding Adrenomedullin Receptor Complex Adrenomedullin Receptor Activity Amylin Receptor 1 Signaling Pathway Amylin Receptor 2 Signaling Pathway Extracellular Vesicle Biogenesis Positive Regulation Of Extracellular Exosome Assembly Actomyosin Contractile Ring Assembly Keratin Filament G Protein-coupled Receptor Activity Postsynaptic Specialization, Intracellular Component Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Adrenomedullin Receptor Signaling Pathway Amylin Receptor Signaling Pathway Copper Ion Import ATP-dependent Protein Disaggregase Activity Regulation Of Extracellular Exosome Assembly Vascular Associated Smooth Muscle Cell Proliferation Response To Sucrose Response To Disaccharide Copper Ion Transmembrane Transporter Activity Maintenance Of Epithelial Cell Apical/basal Polarity
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