KRTAP9-3 and CHRNG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP9-3	CHRNG
Description		keratin associated protein 9-3	cholinergic receptor nicotinic gamma subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Plasma Membrane Acetylcholine-gated Channel Complex Membrane Neuron Projection Synapse Postsynaptic Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Transmembrane Signaling Receptor Activity Monoatomic Ion Channel Activity Extracellular Ligand-gated Monoatomic Ion Channel Activity Protein Binding Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Monoatomic Cation-selective Channel Activity Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process		Skeletal Muscle Contraction Monoatomic Ion Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Monoatomic Ion Transmembrane Transport Membrane Depolarization Regulation Of Postsynaptic Membrane Potential Excitatory Postsynaptic Potential Acetylcholine Receptor Signaling Pathway
Pathways		Keratinization	Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
Drugs
Diseases			Multiple pterygium syndrome, including: Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
GWAS			Refractive error ( 23396134 32231278)
Interacting Genes		135 interacting genes: ADAMTSL4 ALPP ANKS1A ATN1 CARD10 CATSPER1 CCER1 CELF5 CERCAM CHRD CHRNG CNNM3 COL8A1 CRCT1 CREB5 CRH CYSRT1 DCDC2 DMRT3 DOCK2 ECM1 FAM124B FBXO34 FBXW5 GET4 GLRX3 GNE HOXA1 HOXA9 INCA1 ITGB4 JOSD1 KLHL38 KLK8 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-1 KRTAP13-3 KRTAP19-2 KRTAP19-6 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LMNTD2 LNX1 MAPKBP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NPDC1 NR1D2 NR4A3 NTM NUFIP2 OTX1 PAX5 PAX6 PGAP6 PHLDA1 POU4F2 PRKAB2 PTPMT1 PVR RAMP3 RGS20 SH3GLB2 SHFL SLC13A5 SLC23A1 SLC25A18 SMCP SPMIP6 SPRY1 TFAP2D TOX3 TRIM42 TSPAN4 UNC119 VASN VGLL3 WNT11 YY1 ZDHHC1 ZNF414 ZNF439 ZNF440 ZNF497 ZNF575	21 interacting genes: ADAMTSL4 CHRNA1 CYSRT1 KRT31 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP5-9 KRTAP9-3 MDFI MEOX2 NBPF19 NOTCH2NLA SGTA SNX1 SPRY2
Entrez ID		83900	1146
HPRD ID		13950	00009
Ensembl ID		ENSG00000204873	ENSG00000196811
Uniprot IDs		Q9BYQ3	A0A6F7YAP6 P07510
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Protein Binding Tissue Development Hair Cycle	Keratin Filament Intermediate Filament Identical Protein Binding Epidermis Development Structural Constituent Of Skin Epidermis
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