KRTAP3-1 and RECK

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP3-1	RECK
Description		keratin associated protein 3-1	reversion inducing cysteine rich protein with kazal motifs
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Extracellular Region Plasma Membrane Membrane Side Of Membrane Wnt Signalosome
	Molecular Function	Structural Molecule Activity Protein Binding	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Coreceptor Activity Wnt-protein Binding Peptidase Inhibitor Activity
	Biological Process		Blood Vessel Maturation Sprouting Angiogenesis Embryo Implantation Negative Regulation Of Extracellular Matrix Disassembly Wnt Signaling Pathway Extracellular Matrix Organization Negative Regulation Of Cell Migration Embryonic Forelimb Morphogenesis Regulation Of Angiogenesis Canonical Wnt Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Extracellular Matrix Organization
Pathways		Keratinization	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Bipolar disorder (inflammation and infection response interaction) ( 25781172) IgG glycosylation ( 23382691)
Interacting Genes		83 interacting genes: ADAM12 AGXT ANAPC11 BMP7 CDKN1A CELA2B CERK CFP CIMIP1 CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SAXO4 SLC5A5 SMARCC1 SPAG8 SPMIP9 TEKT3 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446	43 interacting genes: ADAM12 BMF C22orf39 CCN3 CEP44 CFP CTH CTIF CYSRT1 DISC1 DYRK1A EFHC2 GLRX3 INCA1 KEAP1 KLHL20 KRT40 KRTAP10-8 KRTAP13-2 KRTAP26-1 KRTAP3-1 LCN1 MEOX2 MLPH MMP9 MTNR1B NBPF19 NDUFB7 NOTCH2NLA NR4A3 NUDT16L1 OXER1 PRIM2 REL SPSB2 SSC4D TCF4 TEKT4 TRIM39 TRIM69 USHBP1 ZNF438 ZNF704
Entrez ID		83896	8434
HPRD ID		13937	05567
Ensembl ID		ENSG00000212901	ENSG00000122707
Uniprot IDs		Q9BYR8	A8K9D8 O95980 Q6P9E2
PDB IDs			8TZP
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratinization Keratin Filament Epidermis Development Axonemal A Tubule Inner Sheath Tissue Development Ventral Spinal Cord Interneuron Differentiation Heart Trabecula Morphogenesis Cellular Response To Cell-matrix Adhesion	Keratin Filament Intermediate Filament
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