GCM2 and KRTAP7-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GCM2	KRTAP7-1
Description		glial cells missing transcription factor 2	keratin associated protein 7-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Intermediate Filament
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Intracellular Calcium Ion Homeostasis Intracellular Phosphate Ion Homeostasis Gliogenesis Positive Regulation Of Transcription By RNA Polymerase II Parathyroid Gland Development
Pathways
Drugs
Diseases
GWAS		Menarche and menopause (age at onset) ( 19448621) Metabolite levels ( 23823483) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		34 interacting genes: CEACAM6 CRX DOK3 ECM1 FHL3 GPSM1 GSC2 HOXA1 HSF2BP HSFY1 HSFY2 JMJD7 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 LHX3 MEOX2 MYOZ3 PAX6 PAX8 PLEKHG4 POU6F2 RBPMS RUSC1 SSBP1 TBX19 TOX3 TRAF1 USP54 WWOX YPEL3 ZMIZ2 ZNF34	37 interacting genes: ARID5A C11orf16 C1orf94 CELF5 CREB5 CRYBA2 DTX2 FAM168A FOXH1 GATA2 GCM2 HGS HNRNPF MKRN3 MYOZ3 OTX1 PITX1 PITX2 PRR13 PSMB1 RANBP3 RHOXF2 RNF38 ROR2 SHARPIN SMARCC1 SNRPC SPAG8 TCF7L2 TEKT4 TFAP2D TLE5 TLX3 TOLLIP VPS37C YTHDF1 ZIC1
Entrez ID		9247	337878
HPRD ID		04758	19546
Ensembl ID		ENSG00000124827	ENSG00000274749
Uniprot IDs		O75603	Q8IUC3
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Sequence-specific Double-stranded DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process DNA Binding Sequence-specific DNA Binding Pituitary Gland Development Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Inner Ear Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Fate Specification Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process SMAD Protein Signal Transduction	DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Transcription Regulator Complex Positive Regulation Of RNA Metabolic Process Chromatin Myoblast Fate Commitment Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Pituitary Gland Development Nucleus Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Embryonic Morphogenesis Gland Development GABAergic Neuron Differentiation DNA Binding Inner Ear Morphogenesis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Axonemal A Tubule Inner Sheath Nuclear Androgen Receptor Binding Ubiquitin Binding Protein Binding R-SMAD Binding Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Embryonic Hindlimb Morphogenesis Regulation Of Metabolic Process Diencephalon Morphogenesis Superior Vena Cava Morphogenesis Subthalamic Nucleus Development Multivesicular Body Assembly MRNA Splice Site Recognition Multivesicular Body Organization
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