GCM2 and HSFY2

Number of citations of the paper that reports this interaction (PubMedID 29892012)
71

Data Source:
BioGRID (two hybrid, two hybrid)

		GCM2	HSFY2
Description		glial cells missing transcription factor 2	heat shock transcription factor Y-linked 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Intracellular Calcium Ion Homeostasis Intracellular Phosphate Ion Homeostasis Gliogenesis Positive Regulation Of Transcription By RNA Polymerase II Parathyroid Gland Development	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Menarche and menopause (age at onset) ( 19448621) Metabolite levels ( 23823483) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		34 interacting genes: CEACAM6 CRX DOK3 ECM1 FHL3 GPSM1 GSC2 HOXA1 HSF2BP HSFY1 HSFY2 JMJD7 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 LHX3 MEOX2 MYOZ3 PAX6 PAX8 PLEKHG4 POU6F2 RBPMS RUSC1 SSBP1 TBX19 TOX3 TRAF1 USP54 WWOX YPEL3 ZMIZ2 ZNF34	9 interacting genes: ATXN1 BPIFA1 CCNK DTX2 GCM2 NFYC OTUD7B TBX6 TOX2
Entrez ID		9247	159119
HPRD ID		04758	13680
Ensembl ID		ENSG00000124827	ENSG00000169953
Uniprot IDs		O75603	Q96LI6
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Sequence-specific Double-stranded DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process DNA Binding Sequence-specific DNA Binding Pituitary Gland Development Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Inner Ear Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Fate Specification Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process SMAD Protein Signal Transduction	Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Regulation Of RNA Metabolic Process Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Cyclin K-CDK13 Complex Cyclin K-CDK12 Complex Immune Response In Nasopharyngeal-associated Lymphoid Tissue Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism DNA-templated Transcription Negative Regulation Of Neuron Maturation Positive Regulation Of Macromolecule Metabolic Process POZ Domain Binding Immune Response In Gut-associated Lymphoid Tissue Nucleus Regulation Of Gene Expression CCAAT-binding Factor Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Gliogenesis Parathyroid Gland Development Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Poly(G) Binding Mesodermal Cell Fate Specification Cyclin/CDK Positive Transcription Elongation Factor Complex Positive Regulation Of TORC2 Signaling Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Neuron Maturation Intracellular Phosphate Ion Homeostasis Somite Rostral/caudal Axis Specification RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Protein K11-linked Deubiquitination Regulation Of Macromolecule Metabolic Process Nuclear Inclusion Body Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Host-mediated Suppression Of Viral Genome Replication Regulation Of TORC2 Signaling
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