ZMIZ2 and PIAS3

Number of citations of the paper that reports this interaction (PMID 20159969)
5

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		ZMIZ2	PIAS3
Gene Name		zinc finger, MIZ-type containing 2	protein inhibitor of activated STAT, 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Nuclear Replication Fork	Nucleus Cytoplasm Dendrite Synapse
	Molecular Function	Protein Binding Zinc Ion Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity	Protein Binding Protein C-terminus Binding Zinc Ion Binding Potassium Channel Regulator Activity Ligase Activity SUMO Transferase Activity Enzyme Binding Protein N-terminus Binding
	Biological Process	Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Response To Hormone Positive Regulation Of Gene Expression Protein Sumoylation Positive Regulation Of Protein Sumoylation Positive Regulation Of Membrane Potential
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: AR ARSJ ASB13 BANP C2orf88 CRCP INTS4 LRRC37A11P MVP NBL1 PIAS3 PIN1 RANBP3 SALL2 SCAMP1 SELV SOCS6 SSX2 TP53 TRAPPC6A	49 interactors: AR ATF7IP C19orf60 CARHSP1 CBS CREM EP300 ESR1 ESR2 GEMIN4 GFI1 GLUL HABP4 HDAC1 HMGA2 MITF NCOA2 NR3C2 OPN1LW PGR PPP1CA PRPF40A PSMC1 RAC1 RELA SATB1 SERBP1 SERPINA10 SIAH1 SIAH2 SKIL SMAD2 SMAD3 SMAD4 SREBF2 STAT3 SUMO1 SUMO2 SUMO3 TBP TRIM27 TRIM32 TRIM55 TRIM63 UBA1 UBE2I ZFHX3 ZMIZ1 ZMIZ2
Entrez ID		83637	10401
HPRD ID		13225	09068
Ensembl ID		ENSG00000122515	ENSG00000131788
Uniprot IDs		E7EWM3 Q8NF64	B3KNI3 Q6IAR4 Q9Y6X2
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Integrin Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Signal Transduction RNA Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromitophagy Sequestering Of BMP From Receptor Via BMP Binding Oligodendrocyte Apoptotic Process Protein Localization Regulation Of Phosphorylation Positive Regulation Of Integrin Biosynthetic Process Negative Regulation Of Monocyte Chemotaxis Negative Regulation Of Helicase Activity Sequestering Of BMP In Extracellular Matrix Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Type I Interferon Production Regulation Of Integrin Biosynthetic Process Negative Regulation Of Phosphorylation Determination Of Dorsal Identity Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process	Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Response To Organic Substance Regulation Of Cellular Process Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Cellular Response To Organic Substance Biosynthetic Process Epithelium Development Regulation Of Signal Transduction Regulation Of Cell Death Regulation Of Signaling Response To Stimulus Cellular Response To Stimulus
Tagcloud ?			achieved atm atr consistently crucial dbc1 deficient diverse establish etoposide finely genotoxic interaction knockdown metabolism modification modifier promoted promotion remarkably senp1 sirt1 sumo sumo1 sumo2 sumoylation switching transactivation ubiquitin
Tagcloud (Difference) ?			achieved atm atr consistently crucial dbc1 deficient diverse establish etoposide finely genotoxic interaction knockdown metabolism modification modifier promoted promotion remarkably senp1 sirt1 sumo sumo1 sumo2 sumoylation switching transactivation ubiquitin
Tagcloud (Intersection) ?