PIAS3 and HABP4

Number of citations of the paper that reports this interaction (PubMedID 16455055)
0

Data Source:
HPRD (two hybrid)

		PIAS3	HABP4
Description		protein inhibitor of activated STAT 3	hyaluronan binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol	Extracellular Region Nucleus Nucleolus Cytoplasm Cytosol Cytoplasmic Stress Granule Cajal Body Sarcoplasm Nuclear Body Nuclear Speck Sarcomere Nuclear Membrane Gemini Of Cajal Bodies
	Molecular Function	Transcription Coregulator Activity Protein Binding Zinc Ion Binding Transferase Activity SUMO Transferase Activity Metal Ion Binding SUMO Ligase Activity	RNA Binding Protein Binding SUMO Binding Ribosome Binding Translation Elongation Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Sumoylation Negative Regulation Of Protein Sumoylation Positive Regulation Of Protein Sumoylation Negative Regulation Of Osteoclast Differentiation Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process	MRNA Processing Regulation Of Translation RNA Splicing PML Body Organization Positive Regulation Of RNA Splicing Positive Regulation Of Translational Initiation Cellular Response To Mechanical Stimulus Ribosome Hibernation
Pathways		SUMOylation of transcription factors SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of DNA replication proteins SUMOylation of immune response proteins Formation of Incision Complex in GG-NER	Platelet degranulation
Drugs			Hyaluronic acid
Diseases
GWAS			Appendicular lean mass ( 33097823) Height ( 25282103 31562340) Hip circumference adjusted for BMI ( 34021172) Household income (MTAG) ( 31844048) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		61 interacting genes: AR ATF7IP CARHSP1 CBS CREBBP CREM EP300 ERG ESR1 ESR2 FOXP2 GEMIN4 GFI1 GLUL HABP4 HDAC1 HMGA2 MITF MORC3 NCOA2 NR3C2 NRIP1 OPN1LW PGR PLIN3 PPP1CA PRPF40A PSMC1 RAC1 RELA REX1BD SATB1 SENP1 SERBP1 SERPINA10 SIAH1 SIAH2 SKIL SMAD2 SMAD3 SMAD4 SNAI2 SNCA SNIP1 SPOP SREBF2 STAT3 STIP1 SUMO1 SUMO2 SUMO3 TBP TRIM27 TRIM32 TRIM55 TRIM63 UBA1 UBE2I ZFHX3 ZMIZ1 ZMIZ2	27 interacting genes: C1QBP CHD3 CRK CRYAA DAXX ENO2 FRA10AC1 HMGXB4 KAT5 OGT PIAS3 PPP1R15A PRKCA PRKCB PRKCD PRKCG PRKCQ PRKCZ PRMT1 RACK1 SRSF9 SYNCRIP TOPORS TP53 UBE2I VIM YBX1
Entrez ID		10401	22927
HPRD ID		09068	13628
Ensembl ID		ENSG00000131788	ENSG00000130956
Uniprot IDs		B3KNI3 Q9Y6X2	Q5JVS0
PDB IDs		4MVT
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Nucleus Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Chromatin Negative Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleoplasm Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Gene Expression RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Regulator Complex Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Enzyme Binding DNA-binding Transcription Factor Activity Transcription Coactivator Binding Protein Sumoylation Positive Regulation Of Macromolecule Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Transcription Cis-regulatory Region Binding Positive Regulation Of Biosynthetic Process Estrogen Response Element Binding Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Chromatin Binding Rhythmic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific SMAD Protein Complex PML Body Sequence-specific DNA Binding Regulation Of MiRNA Transcription Nuclear Steroid Receptor Activity Protein Modification By Small Protein Conjugation	Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Enzyme Binding Regulation Of Metabolic Process Post-transcriptional Regulation Of Gene Expression Protein Kinase C Signaling Positive Regulation Of Biosynthetic Process Nucleus Apoptotic Process Programmed Cell Death Cell Death Regulation Of Programmed Cell Death Intracellular Signal Transduction Regulation Of Insulin Receptor Signaling Pathway Presynaptic Cytosol Regulation Of Protein Metabolic Process Positive Regulation Of Translation Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Translation Cellular Response To Oxygen-containing Compound Negative Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of MRNA Metabolic Process PML Body Positive Regulation Of Cell Communication Positive Regulation Of Signaling Cytosol Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Signal Transduction Histone H3T6 Kinase Activity Positive Regulation Of Protein Metabolic Process Cytoplasm
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