ZMIZ2 and GCM2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZMIZ2	GCM2
Description		zinc finger MIZ-type containing 2	glial cells missing transcription factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion Nuclear Replication Fork	Chromatin Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding SUMO Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II SMAD Protein Signal Transduction	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Intracellular Calcium Ion Homeostasis Intracellular Phosphate Ion Homeostasis Gliogenesis Positive Regulation Of Transcription By RNA Polymerase II Parathyroid Gland Development
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Fasting glucose ( 34059833) General cognitive ability ( 29844566) Hematocrit ( 32888494) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252)	Menarche and menopause (age at onset) ( 19448621) Metabolite levels ( 23823483) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		27 interacting genes: AKAP19 AR ARSJ ASB13 BANP CPNE7 CRCP FRS3 GCM2 INTS4 KPNA4 LRRC37A11P MCPH1 MVP NBL1 PIAS3 PIN1 RANBP3 SALL2 SCAMP1 SELENOV SOCS6 SS18L1 SSX2 SUMO2 TP53 TRAPPC6A	34 interacting genes: CEACAM6 CRX DOK3 ECM1 FHL3 GPSM1 GSC2 HOXA1 HSF2BP HSFY1 HSFY2 JMJD7 KRTAP6-2 KRTAP7-1 KRTAP8-1 LASP1 LHX3 MEOX2 MYOZ3 PAX6 PAX8 PLEKHG4 POU6F2 RBPMS RUSC1 SSBP1 TBX19 TOX3 TRAF1 USP54 WWOX YPEL3 ZMIZ2 ZNF34
Entrez ID		83637	9247
HPRD ID		13225	04758
Ensembl ID		ENSG00000122515	ENSG00000124827
Uniprot IDs		E7EWM3 Q8NF64	O75603
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynaptic Cytosol	DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Sequence-specific Double-stranded DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process DNA Binding Sequence-specific DNA Binding Pituitary Gland Development Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Inner Ear Development Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Fate Specification Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process SMAD Protein Signal Transduction
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