GPR101 and TMEM147

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPR101	TMEM147
Description		G protein-coupled receptor 101	transmembrane protein 147
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GO Annotations	Cellular Component	Plasma Membrane Membrane Receptor Complex	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Nuclear Membrane Protein-containing Complex Multi-pass Translocon Complex
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Protein Binding Ribosome Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway	Protein Localization To Nuclear Inner Membrane Multi-pass Transmembrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062)	Alanine aminotransferase levels ( 33547301) Liver enzyme levels (alanine transaminase) ( 33972514)
Interacting Genes		20 interacting genes: AGPAT4 C1GALT1 CDIPT CYB561A3 DERL3 LAT NDUFB11 ORMDL3 RTP2 SLC35E4 SLC39A9 SLC41A1 SLC61A1 THSD7B TM4SF4 TMEM147 TMEM239 UNC93A UNC93B1 YIPF6	61 interacting genes: ABHD16A ABI3 BIK CD40 CD79A CLDN7 CLN8 CLRN1 CREB3L1 CXCR2 CYB5R3 DPM3 EBP EFNA4 ENPP4 ERGIC3 F11R FAM209A FFAR2 FKBP7 GJA8 GLP1R GOLM1 GPR101 GPR37L1 GPR42 GPR61 HTR2C IL3RA KASH5 LDLRAD1 LEUTX LHFPL2 MTIF3 MUC1 PDCD1LG2 PSCA PVR RMDN3 RNF185 SAR1A SCAMP4 SHISA3 SLC10A1 SLC12A7 SLC13A4 SLC18A1 SLC22A1 SLC22A2 SLC35H1 SUSD3 SYNE4 TACR1 TEX29 TMEM14B TMEM237 TMEM248 TMEM252 TMEM42 TMEM52B TSPAN12
Entrez ID		83550	10430
HPRD ID		02315	17633
Ensembl ID		ENSG00000165370	ENSG00000105677
Uniprot IDs		Q96P66	Q9BVK8
PDB IDs		8W8Q 8W8R 8W8S	6W6L 9C7U 9C7V
Enriched GO Terms of Interacting Partners?		Membrane CDP-diacylglycerol Metabolic Process Intestinal Epithelial Cell Development Columnar/cuboidal Epithelial Cell Development	Membrane Neurotransmitter Reuptake Norepinephrine Uptake Serotonin Uptake Norepinephrine Transport Neurotransmitter Uptake Monoamine Transmembrane Transporter Activity Plasma Membrane G Protein-coupled Receptor Activity Catecholamine Uptake Dopamine Uptake Serotonin Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Protein Binding Xenobiotic Transmembrane Transporter Activity Dopamine Transport Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Monoamine Transport Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Actin-based Cell Projection Neurotransmitter Transport Transmembrane Transporter Activity Prostaglandin Transmembrane Transporter Activity Xenobiotic Transport Meiotic Nuclear Membrane Microtubule Tethering Complex Transmembrane Transport Amine Transport Organic Cation Transmembrane Transporter Activity Azole Transmembrane Transport Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
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