GPR101 and TM4SF4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPR101	TM4SF4
Description		G protein-coupled receptor 101	transmembrane 4 L six family member 4
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Receptor Complex	Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of MAPK Cascade Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway	Tissue Regeneration
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28892062)	Alanine aminotransferase levels ( 33339817 33547301) Alanine transaminase levels ( 29403010) Gallstone disease ( 27094239 30504769) Gamma glutamyl transferase levels ( 29403010 33339817) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Serum alkaline phosphatase levels ( 33547301) Serum uric acid levels ( 30993211) Thyroid stimulating hormone levels ( 30367059 32769997) Urate levels ( 31578528)
Interacting Genes		20 interacting genes: AGPAT4 C1GALT1 CDIPT CYB561A3 DERL3 LAT NDUFB11 ORMDL3 RTP2 SLC35E4 SLC39A9 SLC41A1 SLC61A1 THSD7B TM4SF4 TMEM147 TMEM239 UNC93A UNC93B1 YIPF6	22 interacting genes: APH1B CD79A CLEC17A CMTM2 CREB3 ERGIC3 FATE1 FFAR2 GJB1 GJB4 GJB5 GLP1R GPR101 GPR37L1 GPR42 GPX8 KCNK5 LHFPL5 OPRM1 SLC10A6 TBXA2R TMEM14B
Entrez ID		83550	7104
HPRD ID		02315	07585
Ensembl ID		ENSG00000165370	ENSG00000169903
Uniprot IDs		Q96P66	P48230
PDB IDs		8W8Q 8W8R 8W8S
Enriched GO Terms of Interacting Partners?		Membrane CDP-diacylglycerol Metabolic Process Intestinal Epithelial Cell Development Columnar/cuboidal Epithelial Cell Development	Membrane G Protein-coupled Receptor Activity Connexin Complex Gap Junction Channel Activity Gap Junction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Peptide Receptor Activity G Protein-coupled Receptor Signaling Pathway Plasma Membrane Transmembrane Transport Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Blood Pressure Glucagon-like Peptide 1 Receptor Activity Positive Regulation Of Blood Pressure Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Thromboxane Receptor Activity Thromboxane A2 Signaling Pathway Thromboxane A2 Receptor Activity Positive Regulation Of Deacetylase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Negative Regulation Of Blood Pressure
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