TMEM147 and SLC13A4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM147	SLC13A4
Description		transmembrane protein 147	solute carrier family 13 member 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Nuclear Membrane Protein-containing Complex Multi-pass Translocon Complex	Plasma Membrane Membrane
	Molecular Function	Protein Binding Ribosome Binding	Protein Binding Symporter Activity Solute:sodium Symporter Activity Sodium:sulfate Symporter Activity Transmembrane Transporter Activity
	Biological Process	Protein Localization To Nuclear Inner Membrane Multi-pass Transmembrane Protein Insertion Into ER Membrane	Monoatomic Ion Transport Sodium Ion Transport Sodium Ion Transmembrane Transport Transmembrane Transport Sulfate Transmembrane Transport
Pathways			Sodium-coupled sulphate, di- and tri-carboxylate transporters
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Liver enzyme levels (alanine transaminase) ( 33972514)	Alcoholic chronic pancreatitis ( 28754779) Diverticular disease ( 30177863)
Interacting Genes		61 interacting genes: ABHD16A ABI3 BIK CD40 CD79A CLDN7 CLN8 CLRN1 CREB3L1 CXCR2 CYB5R3 DPM3 EBP EFNA4 ENPP4 ERGIC3 F11R FAM209A FFAR2 FKBP7 GJA8 GLP1R GOLM1 GPR101 GPR37L1 GPR42 GPR61 HTR2C IL3RA KASH5 LDLRAD1 LEUTX LHFPL2 MTIF3 MUC1 PDCD1LG2 PSCA PVR RMDN3 RNF185 SAR1A SCAMP4 SHISA3 SLC10A1 SLC12A7 SLC13A4 SLC18A1 SLC22A1 SLC22A2 SLC35H1 SUSD3 SYNE4 TACR1 TEX29 TMEM14B TMEM237 TMEM248 TMEM252 TMEM42 TMEM52B TSPAN12	26 interacting genes: ACKR2 CBLIF CD79A CDS1 CERS4 DEFB108B DERL3 EFNA5 EOGT ERMP1 FCER1G GJA5 GPR152 GPR61 IER3 IGFBP5 MS4A13 OPRD1 OTOP3 SLC35A4 SLC35E4 SLC38A1 SLC41A1 TMEM147 TMEM60 TRARG1
Entrez ID		10430	26266
HPRD ID		17633	10372
Ensembl ID		ENSG00000105677	ENSG00000164707
Uniprot IDs		Q9BVK8	A0A804HKQ4 Q59HF0 Q9UKG4
PDB IDs		6W6L 9C7U 9C7V
Enriched GO Terms of Interacting Partners?		Membrane Neurotransmitter Reuptake Norepinephrine Uptake Serotonin Uptake Norepinephrine Transport Neurotransmitter Uptake Monoamine Transmembrane Transporter Activity Plasma Membrane G Protein-coupled Receptor Activity Catecholamine Uptake Dopamine Uptake Serotonin Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Protein Binding Xenobiotic Transmembrane Transporter Activity Dopamine Transport Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Monoamine Transport Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Actin-based Cell Projection Neurotransmitter Transport Transmembrane Transporter Activity Prostaglandin Transmembrane Transporter Activity Xenobiotic Transport Meiotic Nuclear Membrane Microtubule Tethering Complex Transmembrane Transport Amine Transport Organic Cation Transmembrane Transporter Activity Azole Transmembrane Transport Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway	Membrane
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