TMEM147 and TMEM252

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM147	TMEM252
Description		transmembrane protein 147	transmembrane protein 252
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Nuclear Membrane Protein-containing Complex Multi-pass Translocon Complex	Membrane
	Molecular Function	Protein Binding Ribosome Binding	Protein Binding
	Biological Process	Protein Localization To Nuclear Inner Membrane Multi-pass Transmembrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Liver enzyme levels (alanine transaminase) ( 33972514)
Interacting Genes		61 interacting genes: ABHD16A ABI3 BIK CD40 CD79A CLDN7 CLN8 CLRN1 CREB3L1 CXCR2 CYB5R3 DPM3 EBP EFNA4 ENPP4 ERGIC3 F11R FAM209A FFAR2 FKBP7 GJA8 GLP1R GOLM1 GPR101 GPR37L1 GPR42 GPR61 HTR2C IL3RA KASH5 LDLRAD1 LEUTX LHFPL2 MTIF3 MUC1 PDCD1LG2 PSCA PVR RMDN3 RNF185 SAR1A SCAMP4 SHISA3 SLC10A1 SLC12A7 SLC13A4 SLC18A1 SLC22A1 SLC22A2 SLC35H1 SUSD3 SYNE4 TACR1 TEX29 TMEM14B TMEM237 TMEM248 TMEM252 TMEM42 TMEM52B TSPAN12	5 interacting genes: LBX1 NEDD4 SLC10A6 TMEM147 YAP1
Entrez ID		10430	169693
HPRD ID		17633	18569
Ensembl ID		ENSG00000105677	ENSG00000181778
Uniprot IDs		Q9BVK8	Q8N6L7
PDB IDs		6W6L 9C7U 9C7V
Enriched GO Terms of Interacting Partners?		Membrane Neurotransmitter Reuptake Norepinephrine Uptake Serotonin Uptake Norepinephrine Transport Neurotransmitter Uptake Monoamine Transmembrane Transporter Activity Plasma Membrane G Protein-coupled Receptor Activity Catecholamine Uptake Dopamine Uptake Serotonin Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Protein Binding Xenobiotic Transmembrane Transporter Activity Dopamine Transport Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Monoamine Transport Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Actin-based Cell Projection Neurotransmitter Transport Transmembrane Transporter Activity Prostaglandin Transmembrane Transporter Activity Xenobiotic Transport Meiotic Nuclear Membrane Microtubule Tethering Complex Transmembrane Transport Amine Transport Organic Cation Transmembrane Transporter Activity Azole Transmembrane Transport Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway	Proline-rich Region Binding Tube Morphogenesis Mesenchyme Development Formation Of Structure Involved In A Symbiotic Process Enterocyte Differentiation Embryonic Heart Tube Morphogenesis Negative Regulation Of Glutamatergic Neuron Differentiation Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Epithelial Tube Morphogenesis Channel Inhibitor Activity Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Sodium Ion Transport Cellular Response To Radiation Phosphothreonine Residue Binding Lateral Mesoderm Development TEAD-YAP Complex Cardiac Muscle Tissue Regeneration Protein Localization To Nuclear Inner Membrane Nuclear Receptor-mediated Corticosteroid Signaling Pathway Bile Acid:sodium Symporter Activity Phosphoserine Residue Binding Beta-2 Adrenergic Receptor Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Transcription Regulator Complex Bud Elongation Involved In Lung Branching Sodium Channel Inhibitor Activity Paraxial Mesoderm Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Endocardial Cushion Development Potassium Channel Inhibitor Activity Branch Elongation Of An Epithelium Intestinal Epithelial Cell Development Regulation Of Nephron Tubule Epithelial Cell Differentiation Notochord Development Female Germ Cell Nucleus Intestinal Epithelial Cell Differentiation Morphogenesis Of An Epithelium Multi-pass Transmembrane Protein Insertion Into ER Membrane Multi-pass Translocon Complex Neuron Fate Determination Negative Regulation Of Sodium Ion Transport Protein Localization To Nuclear Envelope Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Columnar/cuboidal Epithelial Cell Development Interleukin-6-mediated Signaling Pathway Glutamatergic Neuron Differentiation
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