ADPGK and GDF9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		ADPGK	GDF9
Description		ADP dependent glucokinase	growth differentiation factor 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Kinase Activity Transferase Activity Phosphotransferase Activity, Alcohol Group As Acceptor ADP-specific Glucokinase Activity Metal Ion Binding	Cytokine Activity Growth Factor Activity
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Glycolytic Process Glycolytic Process Through Glucose-6-phosphate	Oocyte Growth Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Regulation Of Progesterone Secretion
Pathways		Glycolysis
Drugs
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Hand grip strength ( 29691431) Triglyceride levels ( 28334899) Urate levels ( 23263486) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Asthma ( 31619474)
Interacting Genes		5 interacting genes: GDF9 OGT TADA3 TCAP UBQLN4	45 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 CRIPTO DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TK1 TRIB3 WASHC3
Entrez ID		83440	2661
HPRD ID		12429	03560
Ensembl ID		ENSG00000159322	ENSG00000164404
Uniprot IDs		Q9BRR6	B4DXG3 O60383
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Female Gonad Development Regulation Of Progesterone Secretion Oocyte Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein N-acetylglucosaminyltransferase Complex Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Titin-telethonin Complex Titin Z Domain Binding Detection Of Muscle Stretch Otic Vesicle Formation Myosin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly FATZ Binding Sarcomerogenesis Skeletal Muscle Thin Filament Assembly Regulation Of DNA Repair Negative Regulation Of Autophagosome Maturation Nuclear Proteasome Complex Cytosolic Proteasome Complex Membraneless Organelle Assembly Regulation Of Transcription By Glucose Autophagy K48-linked Polyubiquitin Modification-dependent Protein Binding NSL Complex Cardiac Muscle Hypertrophy In Response To Stress Adult Heart Development Titin Binding ATAC Complex Cardiac Myofibril Assembly Muscle Filament Sliding Regulation Of Autophagosome Maturation Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Proteolysis Actin-myosin Filament Sliding Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Transcription Factor TFTC Complex Acetylglucosaminyltransferase Activity	BMP Receptor Activity Transmembrane Receptor Protein Serine/threonine Kinase Activity Cellular Response To BMP Stimulus Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Ossification Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Activin Receptor Activity, Type II BMP Binding Positive Regulation Of Osteoblast Differentiation Tricuspid Valve Morphogenesis Activin Receptor Signaling Pathway Regulation Of Bone Mineralization BMP Signaling Pathway Transforming Growth Factor Beta Receptor Activity, Type I Negative Regulation Of Chondrocyte Proliferation Regionalization Endochondral Bone Morphogenesis Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Developmental Process Positive Regulation Of SMAD Protein Signal Transduction HFE-transferrin Receptor Complex Mitral Valve Morphogenesis RNA Splicing, Via Transesterification Reactions Regulation Of Ossification Pharyngeal Arch Artery Morphogenesis Osteoblast Differentiation Mesenchyme Development Endocardial Cushion Development Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Positive Regulation Of Programmed Cell Death Pattern Specification Process Regulation Of Osteoblast Differentiation Dorsal/ventral Pattern Formation Cellular Response To Growth Factor Stimulus Regulation Of SMAD Protein Signal Transduction Cellular Developmental Process Cell Differentiation SMN-Sm Protein Complex FAR/SIN/STRIPAK Complex Anterior/posterior Pattern Specification Kinase Activity Precatalytic Spliceosome Atrioventricular Valve Morphogenesis Epithelial Cell Proliferation Protein Binding
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