ARID1A and KLF1

Number of citations of the paper that reports this interaction (PMID 11018012)
66

Data Source:
BioGRID (pull down)

		ARID1A	KLF1
Gene Name		AT rich interactive domain 1A (SWI-like)	Kruppel-like factor 1 (erythroid)
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex NpBAF Complex NBAF Complex	Nuclear Chromatin Nucleus
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Ligand-dependent Nuclear Receptor Binding Nucleosome Binding	Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Neural Tube Closure Cardiac Chamber Development Optic Cup Formation Involved In Camera-type Eye Development Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Forebrain Development Nucleosome Mobilization Glucocorticoid Receptor Signaling Pathway ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Chromatin-mediated Maintenance Of Transcription Placenta Blood Vessel Development Toxin Transport	In Utero Embryonic Development Liver Development Chromatin Remodeling Transcription, DNA-templated Erythrocyte Differentiation Embryonic Hemopoiesis Erythrocyte Maturation Positive Regulation Of Transcription, DNA-templated Cellular Response To Peptide
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: GATA1 HIC1 ITCH KLF1 MLLT1 NEDD4 PGR RARA SMARCA4 SRC TP53	14 interactors: ARID1A CREBBP CSNK2A1 CSNK2A2 EP300 FLI1 HDAC1 PRKACA SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1
Entrez ID		8289	10661
HPRD ID		04319	07197
Ensembl ID		ENSG00000117713	ENSG00000105610
Uniprot IDs		O14497	Q13351
PDB IDs		1RYU	2L2I
Enriched GO Terms of Interacting Partners?		Progesterone Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Embryonic Organ Development Positive Regulation Of Cellular Biosynthetic Process Gland Development Regulation Of Metabolic Process Myeloid Cell Differentiation Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Regulation Of Binding Cellular Response To Organic Substance Hemopoiesis Cell Fate Commitment Organ Development Positive Regulation Of Signal Transduction Immune System Development Regulation Of Signaling Regulation Of Phosphorylation Immune System Process RNA Metabolic Process Regulation Of Protein Metabolic Process Erythrocyte Differentiation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Intracellular Signal Transduction Erythrocyte Homeostasis	Nucleosome Disassembly Chromatin Modification ATP-dependent Chromatin Remodeling Chromatin Organization Chromatin Remodeling Chromosome Organization Nucleosome Organization Chromatin Assembly Or Disassembly Protein Complex Disassembly Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Developmental Process System Development Nervous System Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Interaction With Symbiont RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation By Host Of Viral Transcription Negative Regulation Of Cellular Metabolic Process Organelle Organization Regulation Of Viral Transcription RNA Metabolic Process Anatomical Structure Morphogenesis Regulation Of Metabolic Process Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Regulation Of Viral Process
Tagcloud ?		9p24 actionable atlas barr bystander cd274 cdkn2a classifier comes comprises cpg ebv enrollment epstein fail gastrogenus genomically harbor innocent instability intimately l2 lytic microsatellite mlh1 msi noncoding pdcd1lg2 qualify	acetylation active binds chromatin compromising contributing disappearance erythroid explore expressions facilitating forming gata generation globin interestingly k562 knockdown locus looping near occupancy stabilizing stably structure tal1 though transcribing unclear
Tagcloud (Difference) ?		9p24 actionable atlas barr bystander cd274 cdkn2a classifier comes comprises cpg ebv enrollment epstein fail gastrogenus genomically harbor innocent instability intimately l2 lytic microsatellite mlh1 msi noncoding pdcd1lg2 qualify	acetylation active binds chromatin compromising contributing disappearance erythroid explore expressions facilitating forming gata generation globin interestingly k562 knockdown locus looping near occupancy stabilizing stably structure tal1 though transcribing unclear
Tagcloud (Intersection) ?