EPX and TUBD1

Data Source: HiPPIP (Novel)

		EPX	TUBD1
Name		eosinophil peroxidase	tubulin delta 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule Lumen Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Centriole Cytosol Cytoskeleton Microtubule Cilium Microtubule Cytoskeleton Cell Projection
	Molecular Function	Peroxidase Activity Oxidoreductase Activity Heme Binding Metal Ion Binding Lactoperoxidase Activity	Nucleotide Binding Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Defense Response To Nematode Response To Oxidative Stress Negative Regulation Of Macrophage Cytokine Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-4 Production Defense Response To Bacterium Hydrogen Peroxide Catabolic Process Eosinophil Migration Cellular Oxidant Detoxification	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway
Pathways		Neutrophil degranulation	None
Drugs		Melatonin	Vinblastine
Diseases		Eosinophil peroxidase deficiency	None
GWAS		No GWAS studies recorded	C-reactive protein levels ( 30388399 ) Chronotype ( 30696823 ) Crohn's disease ( 28067908 ) Eosinophil count ( 32888494 ) Eosinophil percentage of granulocytes ( 27863252 ) Hemoglobin levels ( 32327693 ) Inflammatory bowel disease ( 23128233 ) Mean reticulocyte volume ( 32888494 ) Monocyte count ( 29403010 ) Obesity-related traits ( 23251661 ) Red blood cell count ( 32888494 ) Red cell distribution width ( 27863252 28957414 32888494 ) Systolic blood pressure ( 30578418 )
Interacting Genes		None recorded	1 interacting genes: TOP1
Entrez ID		8288	51174
HPRD ID		00576	06297
Ensembl ID		ENSG00000121053	ENSG00000108423
Uniprot IDs		P11678	Q9UJT1
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Response To Purine-containing Compound DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Cellular Response To Luteinizing Hormone Stimulus Dense Fibrillar Component Response To Temperature Stimulus Detection Of Temperature Stimulus Involved In Thermoception Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Fever Generation Temperature-gated Ion Channel Activity Smooth Muscle Contraction Involved In Micturition Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Thermoception Response To Capsazepine Lactoperoxidase Activity Defense Response To Nematode Peptidyl-tRNA Hydrolase Activity