TUBD1 and PTRH2

Data Source: HiPPIP (Novel)

		TUBD1	PTRH2
Name		tubulin delta 1	peptidyl-tRNA hydrolase 2
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centriole Cytosol Cytoskeleton Microtubule Cilium Microtubule Cytoskeleton Cell Projection	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane
	Molecular Function	Nucleotide Binding Structural Constituent Of Cytoskeleton Protein Binding GTP Binding	Peptidyl-tRNA Hydrolase Activity Protein Binding Hydrolase Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway	Apoptotic Process Negative Regulation Of Gene Expression Positive Regulation Of Anoikis Negative Regulation Of Anoikis
Pathways		None	Ub-specific processing proteases
Drugs		Vinblastine	None
GWAS		C-reactive protein levels ( 30388399 ) Chronotype ( 30696823 ) Crohn's disease ( 28067908 ) Eosinophil count ( 32888494 ) Eosinophil percentage of granulocytes ( 27863252 ) Hemoglobin levels ( 32327693 ) Inflammatory bowel disease ( 23128233 ) Mean reticulocyte volume ( 32888494 ) Monocyte count ( 29403010 ) Obesity-related traits ( 23251661 ) Red blood cell count ( 32888494 ) Red cell distribution width ( 27863252 28957414 32888494 ) Systolic blood pressure ( 30578418 )	No GWAS studies recorded
Novel Interactors		6 novel interactors: EPX GJB3 PTRH2 RFX5 TMED1 TRPV1	1 novel interactors: TUBD1
Interacting Genes		1 interacting genes: TOP1	1 interacting genes: TLE5
Entrez ID		51174	51651
HPRD ID		06297	12273
Ensembl ID		ENSG00000108423	ENSG00000141378
Uniprot IDs		Q9UJT1	J3KQ48 Q9Y3E5
PDB IDs		Not available	1Q7S
GO Terms Enriched among Interactors		Response To Purine-containing Compound DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Cellular Response To Luteinizing Hormone Stimulus Dense Fibrillar Component Response To Temperature Stimulus Detection Of Temperature Stimulus Involved In Thermoception Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Fever Generation Temperature-gated Ion Channel Activity Smooth Muscle Contraction Involved In Micturition Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Thermoception Response To Capsazepine Lactoperoxidase Activity Defense Response To Nematode Peptidyl-tRNA Hydrolase Activity	None