TUBD1 and EPX

Data Source: HiPPIP (Novel)

		TUBD1	EPX
Name		tubulin delta 1	eosinophil peroxidase
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centriole Cytosol Cytoskeleton Microtubule Cilium Microtubule Cytoskeleton Cell Projection	Extracellular Region Extracellular Space Secretory Granule Lumen Extracellular Exosome
	Molecular Function	Nucleotide Binding Structural Constituent Of Cytoskeleton Protein Binding GTP Binding	Peroxidase Activity Oxidoreductase Activity Heme Binding Metal Ion Binding Lactoperoxidase Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway	Defense Response To Nematode Response To Oxidative Stress Negative Regulation Of Macrophage Cytokine Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-4 Production Defense Response To Bacterium Hydrogen Peroxide Catabolic Process Eosinophil Migration Cellular Oxidant Detoxification
Pathways		None	Neutrophil degranulation
Drugs		Vinblastine	Melatonin
Diseases		None	Eosinophil peroxidase deficiency
GWAS		C-reactive protein levels ( 30388399 ) Chronotype ( 30696823 ) Crohn's disease ( 28067908 ) Eosinophil count ( 32888494 ) Eosinophil percentage of granulocytes ( 27863252 ) Hemoglobin levels ( 32327693 ) Inflammatory bowel disease ( 23128233 ) Mean reticulocyte volume ( 32888494 ) Monocyte count ( 29403010 ) Obesity-related traits ( 23251661 ) Red blood cell count ( 32888494 ) Red cell distribution width ( 27863252 28957414 32888494 ) Systolic blood pressure ( 30578418 )	No GWAS studies recorded
Interacting Genes		1 interacting genes: TOP1	None recorded
Entrez ID		51174	8288
HPRD ID		06297	00576
Ensembl ID		ENSG00000108423	ENSG00000121053
Uniprot IDs		Q9UJT1	P11678
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Response To Purine-containing Compound DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Cellular Response To Luteinizing Hormone Stimulus Dense Fibrillar Component Response To Temperature Stimulus Detection Of Temperature Stimulus Involved In Thermoception Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Fever Generation Temperature-gated Ion Channel Activity Smooth Muscle Contraction Involved In Micturition Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Thermoception Response To Capsazepine Lactoperoxidase Activity Defense Response To Nematode Peptidyl-tRNA Hydrolase Activity	None