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EPX

Name eosinophil peroxidase
Structure No pdb structure
Novel Interactors 1 novel interactors: TUBD1
Interactors None recorded
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Secretory Granule Lumen
  • Extracellular Exosome
Molecular Function
  • Peroxidase Activity
  • Oxidoreductase Activity
  • Heme Binding
  • Metal Ion Binding
  • Lactoperoxidase Activity
Biological Process
  • Defense Response To Nematode
  • Response To Oxidative Stress
  • Negative Regulation Of Macrophage Cytokine Production
  • Negative Regulation Of Interleukin-10 Production
  • Negative Regulation Of Interleukin-5 Production
  • Positive Regulation Of Interleukin-4 Production
  • Defense Response To Bacterium
  • Hydrogen Peroxide Catabolic Process
  • Eosinophil Migration
  • Cellular Oxidant Detoxification
Pathways
  • Neutrophil degranulation
Drugs
  • Melatonin
Diseases
  • Eosinophil peroxidase deficiency
GWAS No GWAS studies recorded
Entrez ID 8288
HPRD ID 00576
Ensembl ID ENSG00000121053
Uniprot IDs P11678
PDB IDs Not available

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