SPRY4 and TESK1

Number of citations of the paper that reports this interaction (PMID 12027893)
16

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SPRY4	TESK1
Gene Name		sprouty homolog 4 (Drosophila)	testis-specific kinase 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Focal Adhesion Ruffle Membrane	Cytosol
	Molecular Function	Protein Binding	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Multicellular Organismal Development Negative Regulation Of MAP Kinase Activity	Spermatogenesis Peptidyl-tyrosine Phosphorylation Cell Junction Assembly
Pathways			Cell junction organization Regulation of cytoskeletal remodeling and cell spreading by IPP complex components Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 19483681 23666239 23666240)
Protein-Protein Interactions		3 interactors: RAF1 TESK1 ZDHHC17	7 interactors: ABCB4 ARAF CFL1 PFKL SPRY4 YWHAB YY1
Entrez ID		81848	7016
HPRD ID		10466	03470
Ensembl ID		ENSG00000187678	ENSG00000107140
Uniprot IDs		Q9C004	Q15569 Q8NFJ4
PDB IDs		3BUN
Enriched GO Terms of Interacting Partners?		Death-inducing Signaling Complex Assembly
Tagcloud ?		antitumoral cadherin characteristically depletion dysregulated ezh2 homolog interference intron intronic it1 lncrna lncrnas mesenchymal noncoding nsclc nude oncogenesis polycomb repression rescued restored rnas silencing suppressors transcript vimentin xenografted zeste	blastema blastemal crabp2 displaying e15 e17 earliest fzd2 grk7 harboring hdgf igf2 interruption kidneys metanephric microdissected originate orthologous p1 p7 recapitulated revealing robustness timp3 triggering triphasic wilms wnt5b wts
Tagcloud (Difference) ?		antitumoral cadherin characteristically depletion dysregulated ezh2 homolog interference intron intronic it1 lncrna lncrnas mesenchymal noncoding nsclc nude oncogenesis polycomb repression rescued restored rnas silencing suppressors transcript vimentin xenografted zeste	blastema blastemal crabp2 displaying e15 e17 earliest fzd2 grk7 harboring hdgf igf2 interruption kidneys metanephric microdissected originate orthologous p1 p7 recapitulated revealing robustness timp3 triggering triphasic wilms wnt5b wts
Tagcloud (Intersection) ?