SPRY4

Description		sprouty RTK signaling antagonist 4
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Ruffle Membrane Cell Projection
	Molecular Function	Protein Kinase Inhibitor Activity Protein Binding
	Biological Process	Regulation Of Signal Transduction Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Ras Protein Signal Transduction Animal Organ Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases
GWAS		Asthma ( 29273806 31959851) Body mass index ( 28552196) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Gut microbiota (bacterial taxa) ( 27723756) Height ( 31562340) Inflammatory bowel disease ( 23128233) Physiological traits ( 31902109) Systolic blood pressure ( 30578418) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 19483681 23666239 23666240 28604728 28604732)
Interacting Genes		17 interacting genes: ADAM12 COL8A1 CREB5 EFEMP2 FHL2 HOXA1 KLHL38 KRTAP5-11 NUTF2 OTX1 POU4F2 RAF1 RIN3 TESK1 TNS2 VENTX ZDHHC17
Entrez ID		81848
HPRD ID		10466
Ensembl ID		ENSG00000187678
Uniprot IDs		A0A0C4DFS6 Q9C004
PDB IDs		3BUN
Enriched GO Terms of Interacting Partners?
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